61-579-180
CD326 (EpCAM) Monoclonal Antibody (G8.8), PE-eFluor™ 610, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 61-579-180-Each-of-1 | In Stock | ₹ 11,807.28 |
61-579-180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,807.28
GST (18%): ₹ 2,125.31
Total Price: ₹ 13,932.59
Antigen
CD326 (EpCAM)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q99JW5
Gene Symbols
EPCAM
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17075
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
G8.8
Conjugate
PE-eFluor 610
Gene
EPCAM
Gene Alias
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- The G8.8 MAb reacts with the 40 kDa protein mouse EpCAM (epithelial cellular adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326
- The immunogen used to generate the G8.8 antibody was the TE-71 thymic epithelial cell line
- CD326 is expressed on the majority of epithelial cells, and is considered a pan-carcinoma antigen
- CD326 mediates calcium-independent, homophilic, cell-cell adhesion and may function as a growth factor receptor
- The antigen is being used as a target for immunotherapy treatment of human carcinomas
- CD326 binds LAIR-1 (CD305) and LAIR-2 (CD306) to inhibit cellular activation and inflammation
- This epithelial glycoprotein is now recognized as having an important role in tumor biology
- Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule
- Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E
- Ep-CAM mediates Ca2+-independent homotypic interactions
- Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells
- Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation
- Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage
- Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types
- Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.
Compare Similar Items
Show Difference
Antigen: CD326 (EpCAM)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q99JW5
Gene Symbols: EPCAM
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17075
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: G8.8
Conjugate: PE-eFluor 610
Gene: EPCAM
Gene Alias: adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD326 (EpCAM)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q99JW5
Gene Symbols:
EPCAM
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17075
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
G8.8
Conjugate:
PE-eFluor 610
Gene:
EPCAM
Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Phosphotyrosine
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Applications: ELISA, Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: __
Gene Alias: Phosphotyrosine; pTyr; pY
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG
Antigen:
Phosphotyrosine
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Applications:
ELISA, Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Phosphotyrosine; pTyr; pY
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG
Antigen: Phosphotyrosine
Classification: Polyclonal
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol, 4mg/mL BSA and 0.1% ProClin 300; pH 7.4
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Western Blot
Clone: __
Conjugate: HRP
Gene: __
Gene Alias: Phosphotyrosine; pTyr; pY
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG
Antigen:
Phosphotyrosine
Classification:
Polyclonal
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol, 4mg/mL BSA and 0.1% ProClin 300; pH 7.4
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
__
Conjugate:
HRP
Gene:
__
Gene Alias:
Phosphotyrosine; pTyr; pY
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG
Antigen: CD275 (B7-H2)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O75144
Gene Symbols: ICOSLG
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23308
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: MIH12
Conjugate: PE-eFluor 610
Gene: ICOSLG
Gene Alias: AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD275 (B7-H2)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O75144
Gene Symbols:
ICOSLG
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23308
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MIH12
Conjugate:
PE-eFluor 610
Gene:
ICOSLG
Gene Alias:
AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ