63-579-182
CD326 (EpCAM) Monoclonal Antibody (G8.8), Super Bright™ 600, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 63-579-182-Each-of-1 | In Stock | ₹ 32,256.12 |
63-579-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,256.12
GST (18%): ₹ 5,806.102
Total Price: ₹ 38,062.222
Antigen
CD326 (EpCAM)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q99JW5
Gene Symbols
EPCAM
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17075
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
G8.8
Conjugate
Super Bright 600
Gene
EPCAM
Gene Alias
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species
Rat
Quantity
100μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The G8.8 monoclonal antibody reacts with the 40 kDa mouse EpCAM (epithelial cellular adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326
- The immunogen used to generate the G8.8 antibody was the TE-71 thymic epithelial cell line
- CD326 is expressed on the majority of epithelial cells, and is considered a pan-carcinoma antigen
- CD326 mediates calcium-independent, homophilic, cell-cell adhesion and may function as a growth factor receptor
- The antigen is being used as a target for immunotherapy treatment of human carcinomas
- CD326 binds LAIR-1 (CD305) and LAIR-2 (CD306) to inhibit cellular activation and inflammation
- This epithelial glycoprotein is now recognized as having an important role in tumor biology
- Applications Reported: This G8.8 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This G8.8 antibody has been tested by flow cytometric analysis of TE-71 cell line
- This may be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule
- Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E
- Ep-CAM mediates Ca2+-independent homotypic interactions
- Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells
- Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation
- Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage
- Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types
- Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.
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Show Difference
Antigen: CD326 (EpCAM)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q99JW5
Gene Symbols: EPCAM
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17075
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: G8.8
Conjugate: Super Bright 600
Gene: EPCAM
Gene Alias: adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species: Rat
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD326 (EpCAM)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q99JW5
Gene Symbols:
EPCAM
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17075
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
G8.8
Conjugate:
Super Bright 600
Gene:
EPCAM
Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species:
Rat
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: TCR V alpha 2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: B20.1
Conjugate: Super Bright 600
Gene: __
Gene Alias: TCRVA; TCRVA2; V alpha 2; V alpha-2 TCR; Va 2; Va2; Valpha 2; Valpha2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a λ
Antigen:
TCR V alpha 2
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
B20.1
Conjugate:
Super Bright 600
Gene:
__
Gene Alias:
TCRVA; TCRVA2; V alpha 2; V alpha-2 TCR; Va 2; Va2; Valpha 2; Valpha2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a λ
Antigen: CD309 (FLK1)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P35918
Gene Symbols: KDR
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16542
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: Avas12a1
Conjugate: Super Bright 600
Gene: KDR
Gene Alias: 6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
Host Species: Rat
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD309 (FLK1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P35918
Gene Symbols:
KDR
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16542
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Avas12a1
Conjugate:
Super Bright 600
Gene:
KDR
Gene Alias:
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
Host Species:
Rat
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD244
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9BZW8
Gene Symbols: CD244
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51744
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBioC1.7 (C1.7)
Conjugate: Super Bright 600
Gene: CD244
Gene Alias: 2B4; C9.1; CD244; CD244 long isoform; CD244 molecule; Cd244 molecule, natural killer cell receptor 2B4; CD244 natural killer cell receptor 2B4; CD244 short isoform; F730046O15Rik; h2B4; Ly90; NAIL; natural killer cell receptor 2B4; NK cell activation inducing ligand NAIL; NK cell activation-inducing ligand; NK cell receptor 2B4; NK cell type I receptor protein 2B4; NKR Nmrk; NKR2B4; Nmrk; non MHC restricted killing associated; non-MHC restricted killing associated; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4; transmembrane NK cell receptor 2B4
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD244
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9BZW8
Gene Symbols:
CD244
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51744
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBioC1.7 (C1.7)
Conjugate:
Super Bright 600
Gene:
CD244
Gene Alias:
2B4; C9.1; CD244; CD244 long isoform; CD244 molecule; Cd244 molecule, natural killer cell receptor 2B4; CD244 natural killer cell receptor 2B4; CD244 short isoform; F730046O15Rik; h2B4; Ly90; NAIL; natural killer cell receptor 2B4; NK cell activation inducing ligand NAIL; NK cell activation-inducing ligand; NK cell receptor 2B4; NK cell type I receptor protein 2B4; NKR Nmrk; NKR2B4; Nmrk; non MHC restricted killing associated; non-MHC restricted killing associated; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4; transmembrane NK cell receptor 2B4
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ