50-178-40

CD326 (EpCAM) Monoclonal Antibody (VU-1D9), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-178-40-Each-of-1 In Stock ₹ 20,534.40

50-178-40 - Each of 1

₹ 20,534.40

In Stock

Quantity

1

Base Price: ₹ 20,534.40

GST (18%): ₹ 3,696.192

Total Price: ₹ 24,230.592

Antigen

CD326 (EpCAM)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P16422

Gene Symbols

EPCAM

Immunogen

Rec. Human EpCAM (CD326)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

VU-1D9

Conjugate

Unconjugated

Gene

EPCAM

Gene Alias

adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4072

Content And Storage

4° C

Form

Liquid

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Description

  • Description: BMS171 (VU-1D9) specifically reacts with human Ep-CAM, a 40kD epithelial protein expressed on baso-lateral cell surface in many epithelial tissues (but absent from mesothelial tissues)
  • BMS171 differentiates between mesothelioma and carcinoma, a common diagnostic problem
  • EpCAM-1 is a homophilic and Ca2+ independent adhesion molecule that is expressed on the baso-lateral cell surface of many epithelial, but not mesothelial tissues
  • It is expressed de novo in squamous cell carcinoma but is absent in the majority of healthy squamous epithelia
  • EpCAM expression correlates with cell proliferation, dedifferentiation, and the progression of tumorigenicity
  • Applications Tested: Flow Cytometry, Functional Studies (Blocking), Immunohistochemistry (Frozen, Paraffin), Immunoprecipitation, Western Blotting
  • Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule
  • Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E
  • Ep-CAM mediates Ca2+-independent homotypic interactions
  • Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells
  • Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation
  • Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage
  • Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types
  • Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.

Compare Similar Items

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Invitrogen

50-178-40

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Antigen:
CD326 (EpCAM)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P16422

Gene Symbols:
EPCAM

Immunogen:
Rec. Human EpCAM (CD326)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
VU-1D9

Conjugate:
Unconjugated

Gene:
EPCAM

Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4072

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

50-178-41

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Antigen:
CD154 (CD40 Ligand)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P27548

Gene Symbols:
CD40LG

Immunogen:
Rec. Mouse CD40L

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Functional Assay

Clone:
MR1

Conjugate:
Unconjugated

Gene:
CD40LG

Gene Alias:
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5

Host Species:
Armenian Hamster

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
21947

Content And Storage:
4° C

Form:
Liquid

Img

Sigma Aldrich Fine Chemicals Biosciences

50-178-4106

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Invitrogen

50-178-42

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Antigen:
EMAP II

Classification:
Polyclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q12904

Gene Symbols:
Aimp1

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
__

Conjugate:
Unconjugated

Gene:
Aimp1

Gene Alias:
9830137A06Rik; aaRS-interacting multifunctional protein 1; AIMP1; AIMP1/p43; AIMP1-PA; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; aminoacyl tRNA synthetase complex interacting multifunctional protein 1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; aminoacyl-tRNA synthetase-interacting multifunctional protein 1; ARS inducible multifunctional protein 1; ARS-interacting multifunctional protein 1; CG8235; CG8235-PA; Dmel\CG8235; Dmel_CG8235; EMAP2; EMAP-2; EMAPII; EMAP-II; endothelial monocyte activating polypeptide 2; endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; endothelial-monocyte activating polypeptide II; HLD3; mca1; multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; p43; SCYE1; Small inducible cytokine subfamily E member 1; small inducible cytokine subfamily E, member 1; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9255

Content And Storage:
4° C

Form:
Liquid