53-669-642

Syk Monoclonal Antibody (4D10.1), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 53-669-642-Each In Stock ₹ 26,579.21

53-669-642 - Each

₹ 26,579.21

In Stock

Quantity

1

Base Price: ₹ 26,579.21

GST (18%): ₹ 4,784.258

Total Price: ₹ 31,363.468

Antigen

Syk

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P43405

Gene Symbols

Syk

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6850

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

4D10.1

Conjugate

Alexa Fluor 488

Gene

Syk

Gene Alias

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases
  • SYK may also play a role in cancer
  • Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
  • Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
  • These kinases also help to activate Syk by phosphorylation of its activation loop.

Compare Similar Items

Show Difference

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Invitrogen

53-669-642

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Antigen:
Syk

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P43405

Gene Symbols:
Syk

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6850

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
4D10.1

Conjugate:
Alexa Fluor 488

Gene:
Syk

Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

MilliporeSigma™

53-701-15MG

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Protect from light

Form:
Oil

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
5 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

MilliporeSigma™

53-701-25MG

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Protect from light

Form:
Oil

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
5 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Fischer Scientific

53-702-10KU

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
Lyophilized from a solution containing calcium acetate as a stabilizer

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store at+2°C to+8°C

Form:
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Applications:
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Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
10kU

Primary or Secondary:
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Target Species:
__

Product Type:
__

Isotype:
__