Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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CEACAM5/CD66e
0.2mg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Unconjugated
Mouse
Cancer, Cellular Markers, Immunology
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100
CEACAM5
IgG1 κ
Protein A or G purified
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix
C66/1030
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml
Monoclonal
Purified
RUO
Human
P06731
1048
Recombinant full-length human CEA protein
Primary
Store at 4C.