5540279

Semaphorin 4D/CD100 Antibody (133-1C6), Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Semaphorin 4D/CD100

Concentration

0.2 mg/mL

Applications

Flow Cytometry, Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Apoptosis, Immunology

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

A8, CD100 antigen, CD100M-sema-G, coll-4, FLJ33485, FLJ34282, FLJ39737, FLJ46484, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, 4D, MGC169138, MGC169141, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4D, semaphorin-4D

Gene Symbols

SEMA4D

Isotype

IgM κ

Purification Method

Protein A or G purified

Test Specificity

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Clone

133-1C6

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Baboon, Equine (Negative)

Gene Accession No.

Q92854, Q92854

Gene ID (Entrez)

10507

Immunogen

PHA stimulated human peripheral blood lymphocytes.

Primary or Secondary

Primary

Content And Storage

Store at 4C.

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Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence Semaphorin 4D/CD100 Monoclonal specifically detects Semaphorin 4D/CD100 in Human, Baboon, Equine (Negative) samples
  • It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

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Fischer Scientific

5540279

Mouse Monoclonal Antibody has been ...


Antigen:
Semaphorin 4D/CD100

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Immunology

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
A8, CD100 antigen, CD100M-sema-G, coll-4, FLJ33485, FLJ34282, FLJ39737, FLJ46484, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, 4D, MGC169138, MGC169141, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4D, semaphorin-4D

Gene Symbols:
SEMA4D

Isotype:
IgM κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Clone:
133-1C6

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Baboon, Equine (Negative)

Gene Accession No.:
Q92854, Q92854

Gene ID (Entrez):
10507

Immunogen:
PHA stimulated human peripheral blood lymphocytes.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Img

Fischer Scientific

5540298

Mouse Monoclonal Antibody...


Antigen:
SHBG

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Vision

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
ABPTestosterone-estrogen-binding globulin, androgen binding protein, MGC126834, MGC138391, SBP, sex hormone-binding globulin, Sex steroid-binding protein, TeBG, Testis-specific androgen-binding protein, testosterone-binding beta-globulin, Testosterone-estradiol-binding globulin

Gene Symbols:
SHBG

Isotype:
IgG1

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Clone:
SPM605

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
__

Gene ID (Entrez):
6462

Immunogen:
Recombinant full-length human SHBG protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Img

Fischer Scientific

5540298

Mouse Monoclonal Antibody...


Antigen:
SHBG

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Vision

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
ABPTestosterone-estrogen-binding globulin, androgen binding protein, MGC126834, MGC138391, SBP, sex hormone-binding globulin, Sex steroid-binding protein, TeBG, Testis-specific androgen-binding protein, testosterone-binding beta-globulin, Testosterone-estradiol-binding globulin

Gene Symbols:
SHBG

Isotype:
IgG1

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Clone:
SPM605

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
__

Gene ID (Entrez):
6462

Immunogen:
Recombinant full-length human SHBG protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Img

Fischer Scientific

5540298

Mouse Monoclonal Antibody...


Antigen:
SHBG

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Vision

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
ABPTestosterone-estrogen-binding globulin, androgen binding protein, MGC126834, MGC138391, SBP, sex hormone-binding globulin, Sex steroid-binding protein, TeBG, Testis-specific androgen-binding protein, testosterone-binding beta-globulin, Testosterone-estradiol-binding globulin

Gene Symbols:
SHBG

Isotype:
IgG1

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Clone:
SPM605

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
__

Gene ID (Entrez):
6462

Immunogen:
Recombinant full-length human SHBG protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.