61-063-942
CD63 Monoclonal Antibody (H5C6), PE-eFluor™ 610, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 61-063-942-Each | In Stock | ₹ 28,290.41 |
61-063-942 - Each
In Stock
Quantity
1
Base Price: ₹ 28,290.41
GST (18%): ₹ 5,092.274
Total Price: ₹ 33,382.684
Antigen
CD63
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P08962
Gene Symbols
CD63
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
967
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
H5C6
Conjugate
PE-eFluor 610
Gene
CD63
Gene Alias
C75951, CD 63, Cd63, CD63 antigen, CD63 antigen (melanoma 1 antigen), Cd63 molecule, CD63 protein, granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, lysosome-associated membrane glycoprotein 3, mast cell antigen AD1, ME491, melanoma 1 antigen, melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, TSPAN30, tspan-30
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: This H5C6 monoclonal antibody reacts with human CD63, a type III member of the tetraspanin family of transmembrane proteins
- CD63 is expressed intracellularly on lysosomes, endosomes, and granules of resting platelets and basophils
- However, cell surface expression of CD63 can be detected on activated basophils and platelets, monocytes, macrophages, and granulocytes
- This receptor is also expressed on endothelial cells, fibroblasts, and smooth muscle cells
- Studies have demonstrated that CD63 associates with integrins (VLA-3 and VLA-6) and TIMP-1 to mediate the allergic response
- Applications Reported: This H5C6 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This H5C6 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (1.0 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- PE-eFluor 610 can be excited with laser lines from 488-561 nm and emits at 607 nm
- We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red)
- Please make sure that your instrument is capable of detecting this fluorochrome
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types
- CD63 is also present in the plasma membrane, usually following cell activation
- Hence, CD63 has become a widely used basophil activation marker
- In mast cells, however, CD63 exposition does not need their activation
- CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels
- CD63 also serves as a T-cell costimulation molecule
- Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas
- CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation
- CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells
- CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40
- Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
Compare Similar Items
Show Difference
Antigen: CD63
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P08962
Gene Symbols: CD63
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 967
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: H5C6
Conjugate: PE-eFluor 610
Gene: CD63
Gene Alias: C75951, CD 63, Cd63, CD63 antigen, CD63 antigen (melanoma 1 antigen), Cd63 molecule, CD63 protein, granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, lysosome-associated membrane glycoprotein 3, mast cell antigen AD1, ME491, melanoma 1 antigen, melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, TSPAN30, tspan-30
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD63
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P08962
Gene Symbols:
CD63
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
967
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
H5C6
Conjugate:
PE-eFluor 610
Gene:
CD63
Gene Alias:
C75951, CD 63, Cd63, CD63 antigen, CD63 antigen (melanoma 1 antigen), Cd63 molecule, CD63 protein, granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, lysosome-associated membrane glycoprotein 3, mast cell antigen AD1, ME491, melanoma 1 antigen, melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, TSPAN30, tspan-30
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD64
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P12314
Gene Symbols: FCGR1A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2209
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 10.1
Conjugate: PE-eFluor 610
Gene: FCGR1A
Gene Alias: AI323638; AV092959; CD64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; Fcg1; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRI; FcgammaRIa; Fcgr1; FCGR1A; Fcgr1b; FcgRI; FCRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; high affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I; IgG high affinity Fc receptor; IGGHAFC; RP11-196G18.2
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD64
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P12314
Gene Symbols:
FCGR1A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2209
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
10.1
Conjugate:
PE-eFluor 610
Gene:
FCGR1A
Gene Alias:
AI323638; AV092959; CD64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; Fcg1; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRI; FcgammaRIa; Fcgr1; FCGR1A; Fcgr1b; FcgRI; FCRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; high affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I; IgG high affinity Fc receptor; IGGHAFC; RP11-196G18.2
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD68
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P31996
Gene Symbols: Cd68
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12514
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: FA-11
Conjugate: PE-eFluor 610
Gene: Cd68
Gene Alias: CD68, CD68 antigen, CD68 molecule, GP110, Lamp4, macrophage antigen CD68, macrosialin, Scard1, scavenger receptor class D, member 1, similar to CD68 antigen
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD68
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P31996
Gene Symbols:
Cd68
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12514
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
FA-11
Conjugate:
PE-eFluor 610
Gene:
Cd68
Gene Alias:
CD68, CD68 antigen, CD68 molecule, GP110, Lamp4, macrophage antigen CD68, macrosialin, Scard1, scavenger receptor class D, member 1, similar to CD68 antigen
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD69
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P37217
Gene Symbols: CD69
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12515
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: H1.2F3
Conjugate: PE-eFluor 610
Gene: CD69
Gene Alias: 5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
Host Species: Armenian Hamster
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD69
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P37217
Gene Symbols:
CD69
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12515
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
H1.2F3
Conjugate:
PE-eFluor 610
Gene:
CD69
Gene Alias:
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
Host Species:
Armenian Hamster
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG