62-587-842
CD314 (NKG2D) Monoclonal Antibody (1D11), Super Bright™ 436, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 62-587-842-Each-of-1 | In Stock | ₹ 31,486.08 |
62-587-842 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,486.08
GST (18%): ₹ 5,667.494
Total Price: ₹ 37,153.574
Antigen
CD314 (NKG2D)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P26718
Gene Symbols
Klrk1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22914
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
1D11
Conjugate
Super Bright 436
Gene
Klrk1
Gene Alias
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The 1D11 monoclonal antibody reacts with the human NKG2D, a 42 kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells
- Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors
- The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma
- 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells
- 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells
- Applications Reported: This 1D11 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 1D11 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm
- We recommend using a 450/50 bandpass filter, or equivalent
- Please make sure that your instrument is capable of detecting this fluorochrome
- Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation
- NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function
- The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain
- The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
Compare Similar Items
Show Difference
Antigen: CD314 (NKG2D)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P26718
Gene Symbols: Klrk1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22914
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 1D11
Conjugate: Super Bright 436
Gene: Klrk1
Gene Alias: CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD314 (NKG2D)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P26718
Gene Symbols:
Klrk1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22914
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
1D11
Conjugate:
Super Bright 436
Gene:
Klrk1
Gene Alias:
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD314 (NKG2D)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O54709
Gene Symbols: Klrk1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27007
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CX5
Conjugate: Super Bright 436
Gene: Klrk1
Gene Alias: CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species: Rat
Quantity: 25μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD314 (NKG2D)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O54709
Gene Symbols:
Klrk1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27007
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CX5
Conjugate:
Super Bright 436
Gene:
Klrk1
Gene Alias:
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species:
Rat
Quantity:
25μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD314 (NKG2D)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O54709
Gene Symbols: Klrk1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27007
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CX5
Conjugate: Super Bright 436
Gene: Klrk1
Gene Alias: CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species: Rat
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD314 (NKG2D)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O54709
Gene Symbols:
Klrk1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27007
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CX5
Conjugate:
Super Bright 436
Gene:
Klrk1
Gene Alias:
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species:
Rat
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Integrin alpha 4 beta 7 (LPAM-1)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P26011, Q00651
Gene Symbols: Itga4, Itgb7
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16401, 16421
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: DATK32 (DATK-32)
Conjugate: Super Bright 436
Gene: Itgb7
Gene Alias: CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Integrin alpha 4 beta 7 (LPAM-1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P26011, Q00651
Gene Symbols:
Itga4, Itgb7
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16401, 16421
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
DATK32 (DATK-32)
Conjugate:
Super Bright 436
Gene:
Itgb7
Gene Alias:
CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ