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62137942

CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), Super Bright™ 436, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size	SKU	Availability	Price
Each of 1	62137942-Each-of-1	In Stock	₹ 30,972.72

62137942 - Each of 1

₹ 30,972.72

In Stock

Quantity

Base Price: ₹ 30,972.72

GST (18%): ₹ 5,575.09

Total Price: ₹ 36,547.81

Antigen

CD137 (4-1BB)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q07011

Gene Symbols

TNFRSF9

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3604

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

4B4 (4B4-1)

Conjugate

Super Bright 436

Gene

TNFRSF9

Gene Alias

4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Related Products

Description

Description: This 4B4 (4B4-1) monoclonal antibody reacts with human CD137 (also known as 4-1BB or TNFRSF9), which is an inducible member of the TNFR family of costimulatory molecules expressed on T cells, natural killer cells, dendritic cells, granulocytes, and mast cells
Involved in recruiting TNFR-associated factors (TRAF) 1 and 2, CD137 signaling plays a role in T cell activation, maintaining the survival of activated and CD8 memory T cells, as well as suppressing myelopoiesis and dendritic cell development
Stimulation of this receptor has also been shown to promote expansion of CD4+CD25+ T regulatory cells ex vivo
The ligand for CD137, 4-1BBL, is found on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells
Applications Reported: This 4B4 (4B4-1) antibody has been reported for use in flow cytometric analysis
Applications Tested: This 4B4 (4B4-1) antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
This can be used at 5 μL (0.5 μg) per test
A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
Cell number should be determined empirically but can range from 10 5 to 10 8 cells/test
Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm
We recommend using a 450/50 bandpass filter, or equivalent
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells
Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells
CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development
Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival
Soluble forms of CD137 may provide negative control mechanism for some immune responses.

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Invitrogen

62137942

Antigen:

CD137 (4-1BB)

Classification:

Monoclonal

Concentration:

5 μL/Test

Formulation:

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:

Q07011

Gene Symbols:

TNFRSF9

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

3604

Content And Storage:

4° C, store in dark, DO NOT FREEZE!

Form:

Liquid

Applications:

Flow Cytometry

Clone:

4B4 (4B4-1)

Conjugate:

Super Bright 436

Gene:

TNFRSF9

Gene Alias:

4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species:

Mouse

Quantity:

100 Tests

Primary or Secondary:

Primary

Target Species:

Human

Product Type:

Antibody

Isotype:

IgG1 κ

Sigma Aldrich

62139

≥95.0% (sum of enantiomers, GC)...

Antigen:

Classification:

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Clone:

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Invitrogen

62140182

Antigen:

CD140a (PDGFRA)

Classification:

Monoclonal

Concentration:

0.2 mg/mL

Formulation:

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:

P26618

Gene Symbols:

PDGFRA

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

18595

Content And Storage:

4° C, store in dark, DO NOT FREEZE!

Form:

Liquid

Applications:

Flow Cytometry

Clone:

APA5

Conjugate:

Super Bright 436

Gene:

PDGFRA

Gene Alias:

AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140A; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA

Host Species:

Rat

Quantity:

100 μg

Primary or Secondary:

Primary

Target Species:

Mouse

Product Type:

Antibody

Isotype:

IgG2a κ

Sigma Aldrich

62143

96.0-102.0% (HPLC)...

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Classification:

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CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), Super Bright™ 436, eBioscience™, Invitrogen™

Select a Size

Select a Size

Properties

Antigen

Classification

Concentration

Formulation

Gene Accession No.

Gene Symbols

Purification Method

Regulatory Status

Gene ID (Entrez)

Content And Storage

Form

Applications

Clone

Conjugate

Gene

Gene Alias

Host Species

Quantity

Primary or Secondary

Target Species

Product Type

Isotype

Related Products

Invitrogen

Invitrogen

Invitrogen

Invitrogen

Invitrogen

Invitrogen

Invitrogen

Invitrogen

Description

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Invitrogen

Sigma Aldrich

Invitrogen

Sigma Aldrich