67-045-742

CD45RO Monoclonal Antibody (UCHL1), Super Bright™ 702, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 67-045-742-Each-of-1 In Stock ₹ 31,657.20

67-045-742 - Each of 1

₹ 31,657.20

In Stock

Quantity

1

Base Price: ₹ 31,657.20

GST (18%): ₹ 5,698.296

Total Price: ₹ 37,355.496

Antigen

CD45RO

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P08575

Gene Symbols

PTPRC

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

UCHL1

Conjugate

Super Bright 702

Gene

PTPRC

Gene Alias

B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: The UCHL1 monoclonal antibody reacts with human CD45RO, a 180 kDa isoform of CD45
  • CD45RO is expressed by most thymocytes, activated memory T cells, granulocytes and monocytes
  • CD22 is a ligand for CD45RO
  • Expression of CD45RO and CD45RA is used commonly to discriminate subsets of peripheral T cells
  • Applications Reported: This UCHL1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This UCHL1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
  • This may be used at 5 μL (1 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Super Bright 702 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 702 nm
  • We recommend using a 710/50 bandpass filter
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product No
  • SB-4401) to minimize any non-specific polymer interactions
  • Please refer to the datasheet for Super Bright Staining Buffer for more information
  • Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
  • Please protect this vial and stained samples from light
  • CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein
  • CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
  • CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45RO is expressed on macrophages, CD8+ T cells, activated T cells and myeloma cells
  • Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.

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Invitrogen

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Antigen:
CD45RO

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
UCHL1

Conjugate:
Super Bright 702

Gene:
PTPRC

Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

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Fischer Scientific

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Antigen:
CD48

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P18181

Gene Symbols:
Cd48

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12506

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HM48-1

Conjugate:
Super Bright 702

Gene:
Cd48

Gene Alias:
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1

Host Species:
Armenian Hamster

Quantity:
25μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

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Antigen:
CD48

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P18181

Gene Symbols:
Cd48

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12506

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HM48-1

Conjugate:
Super Bright 702

Gene:
Cd48

Gene Alias:
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1

Host Species:
Armenian Hamster

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Antigen:
CD49d (Integrin alpha 4)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P13612

Gene Symbols:
ITGA4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3676

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
9F10

Conjugate:
Super Bright 702

Gene:
ITGA4

Gene Alias:
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ