7069057

CD144 (VE-cadherin) Monoclonal Antibody (eBioBV13 (BV13)), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD144 (VE-cadherin)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Gene Symbols

CDH5

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

CDH5

Clone

eBioBV13 (BV13)

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Conjugate

Biotin

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P55284

Gene ID (Entrez)

12562

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144)
  • VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail
  • VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions
  • VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures
  • Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells
  • Applications Reported: This eBioBV13 (BV13) antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistology staining of frozen tissue sections
  • Applications Tested: This eBioBV13 (BV13) antibody has been tested by flow cytometric analysis of bEnd.3 cells
  • This can be used at less than or equal to 0.25 μg This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer
  • VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail
  • Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions
  • An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.

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Show Difference

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7069057

Rat Monoclonal Antibody...


Antigen:
CD144 (VE-cadherin)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Gene Symbols:
CDH5

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CDH5

Clone:
eBioBV13 (BV13)

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P55284

Gene ID (Entrez):
12562

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
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Form:
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Regulatory Status:
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Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1

Gene Symbols:
L1CAM

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
L1CAM

Clone:
eBio5G3 (5G3)

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Conjugate:
Biotin

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P32004

Gene ID (Entrez):
3897

Isotype:
IgG2a

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Gene Alias:
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Gene Symbols:
Ccr7

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Ccr7

Clone:
4B12

Applications:
Flow Cytometry

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P47774

Gene ID (Entrez):
12775

Isotype:
IgG2a κ

Purification Method:
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Antigen:
CD317 (BST2, PDCA-1)

Concentration:
0.5 mg/mL

Classification:
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Form:
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Regulatory Status:
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Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
2310015I10Rik; bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN

Gene Symbols:
Bst2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
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Clone:
eBio927

Applications:
Flow Cytometry

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q8R2Q8

Gene ID (Entrez):
69550

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody