MUC5AC Antibody (MUC5AC/917) - Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Mucin 5AC
Concentration
1 mg/mL
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Extracellular Matrix
Formulation
PBS with No Preservative
Gene ID (Entrez)
4586
Immunogen
Recombinant human MUC5AC protein
Primary or Secondary
Primary
Content And Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen
641 kDa
Clone
MUC5AC/917
Dilution
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human, Rat (Negative)
Gene Alias
gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols
MUC5AC
Isotype
IgG1 κ
Purification Method
Protein A or G purified
Test Specificity
Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Related Products
Description
- MUC5AC Monoclonal specifically detects MUC5AC in Human, Rat (Negative) samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, CyTOF-ready.
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Antigen: Mucin 5AC
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Extracellular Matrix
Formulation: PBS with No Preservative
Gene ID (Entrez): 4586
Immunogen: Recombinant human MUC5AC protein
Primary or Secondary: Primary
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 641 kDa
Clone: MUC5AC/917
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Rat (Negative)
Gene Alias: gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols: MUC5AC
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Antigen: Napsin A
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cancer, Cell Biology, Cellular Markers
Formulation: PBS with No Preservative
Gene ID (Entrez): 9476
Immunogen: Recombinant fragment of human Napsin-A protein
Primary or Secondary: Primary
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 37 kDa
Clone: NAPSA/1238
Dilution: Western Blot 1 - 2 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: Asp 4, ASP4, Aspartyl protease 4, EC 3.4.23, EC 3.4.23.-, EC 3.4.23.15, EC 3.4.23.3, EC 3.4.23.5, KAP, Kdap, NAP1napsin-A, NAPApronapsin A, NAPSA, napsin A aspartic peptidase, napsin-1, SNAPA, TA01/TA02
Gene Symbols: NAPSA
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
Antigen: N-Cadherin
Concentration: 0.2 mg/mL
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cancer, Cell Cycle and Replication, Cellular Markers, Extracellular Matrix, Phospho Specific, Plasma Membrane Markers, Signal Transduction
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez): 1000
Immunogen: Recombinant human N-cadherin extracellular domain (exact sequence is proprietary)
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Molecular Weight of Antigen: 135 kDa
Clone: 8C11
Dilution: Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Alias: cadherin 2, N-cadherin (neuronal), cadherin 2, type 1, N-cadherin (neuronal), cadherin-2, CD325, CD325 antigen, CDHNcalcium-dependent adhesion protein, neuronal, CDw325, N-cadherin, NCADN-cadherin 1, Neural cadherin, neural-cadherin
Gene Symbols: CDH2
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: __