7092512
CD279 Mouse anti-Human, FITC, Clone: MIH4, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD279
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human PD-1 Transfected Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
MIH4
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Related Products
Description
- The MIH4 monoclonal antibody specifically binds to the program death 1 (PD-1) receptor CD279, a member of the Ig superfamily
- CD279 is an immunoregulatory receptor expressed on activated T cells, B cells and myeloid cells
- Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
- It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
- PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
- Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
- Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
- The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.
Compare Similar Items
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Antigen: CD279
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human PD-1 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MIH4
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Antigen:
CD279
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human PD-1 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MIH4
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Antigen: CD28
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Hamster
Target Species: Mouse
Immunogen: Mouse EL-4 (T-cell lymphoma) Cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 37.51
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2 λ1
Purification Method: Affinity Purified
Description: __
Antigen:
CD28
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Hamster
Target Species:
Mouse
Immunogen:
Mouse EL-4 (T-cell lymphoma) Cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
37.51
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2 λ1
Purification Method:
Affinity Purified
Description:
__
Antigen: CD28
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human CD28 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: CD28.2
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: CD28 antigen; T44; Tp44; TP44
Antigen:
CD28
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human CD28 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
CD28.2
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
CD28 antigen; T44; Tp44; TP44
Antigen: CD3 Molecular Complex
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: γδ TCR-positive T-T hybridoma D1
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 17A2
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG2b κ
Purification Method: Affinity Purified
Description: __
Antigen:
CD3 Molecular Complex
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
γδ TCR-positive T-T hybridoma D1
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
17A2
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG2b κ
Purification Method:
Affinity Purified
Description:
__