7092514

CD28 Hamster anti-Mouse, PE, Clone: 37.51, BD

Hamster Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD28

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Hamster

Target Species

Mouse

Immunogen

Mouse EL-4 (T-cell lymphoma) Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

37.51

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2 λ1

Purification Method

Affinity Purified

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Description

  • The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T cells, and at even lower density on NK cells
  • The expression of CD28, in splenocytes and thymocytes, has been reported to increase after activation
  • CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast cells
  • It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes
  • CD28 is a costimulatory receptor; its ligands include CD80 (B7-1) and CD86 (B7-2)
  • The 37.51 mAb augments proliferation and cytokine production by activated T and NK cells and can provide a costimulatory signal for CTL induction
  • There is considerable evidence that CD28 is a costimulatory receptor involved in many, but not all, T cell-dependent immune responses.

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Show Difference

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Fischer Scientific

7092514

Hamster Monoclonal Antibody...


Antigen:
CD28

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Hamster

Target Species:
Mouse

Immunogen:
Mouse EL-4 (T-cell lymphoma) Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
37.51

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2 λ1

Purification Method:
Affinity Purified

Img

Fischer Scientific

7092515

Mouse Monoclonal Antibody...


Antigen:
CD28

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human CD28 Transfected Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
CD28.2

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

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7092520

Rat Monoclonal Antibody...


Antigen:
CD3 Molecular Complex

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
γδ TCR-positive T-T hybridoma D1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
17A2

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

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7092520

Rat Monoclonal Antibody...


Antigen:
CD3 Molecular Complex

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
γδ TCR-positive T-T hybridoma D1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
17A2

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified