7092814

TRA-1-81 Antigen Mouse anti-Human, PE, Clone: TRA-1-81, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

TRA-1-81 Antigen

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Target Species

Human

Immunogen

Human Embryonal Carcinoma Cell Line

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

TRA-1-81

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgM κ

Purification Method

Affinity Purified

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Description

  • The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein
  • The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21
  • The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation
  • The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells
  • As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.

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Antigen:
TRA-1-81 Antigen

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
Human Embryonal Carcinoma Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
TRA-1-81

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgM κ

Purification Method:
Affinity Purified

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Isotype:
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Purification Method:
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