7105377

EGF R/ErbB1 Mouse, Clone: B1D8, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

EGFR

Dilution

Flow Cytometry 0.5-1ug/million cells, Immunoprecipitation 0.5-1ug/500ug protein lysate

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Mouse (Negative), Rat (Negative)

Gene Accession No.

P00533

Gene ID (Entrez)

1956

Immunogen

Microsomes from A431 cells

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Clone

B1D8

Applications

Flow Cytometry, Immunoprecipitation

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Gene Symbols

EGFR

Isotype

IgG2a κ

Purification Method

Protein A purified

Test Specificity

This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin.

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Description

  • EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative), Rat (Negative) samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunoaffinity Purification.

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Img

Fischer Scientific

7105377

Mouse Monoclonal Antibody has been ...


Antigen:
EGFR

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunoprecipitation 0.5-1ug/500ug protein lysate

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse (Negative), Rat (Negative)

Gene Accession No.:
P00533

Gene ID (Entrez):
1956

Immunogen:
Microsomes from A431 cells

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
B1D8

Applications:
Flow Cytometry, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Gene Symbols:
EGFR

Isotype:
IgG2a κ

Purification Method:
Protein A purified

Test Specificity:
This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin.

Img

Fischer Scientific

7105379

Mouse Monoclonal Antibody...


Antigen:
FGF-23

Dilution:
ELISA, Functional

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
Q9GZV9

Gene ID (Entrez):
8074

Immunogen:
Recombinant human FGF23 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
FGF23/638

Applications:
ELISA, Functional Assay

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Angiogenesis, Cancer

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ADHR, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

Gene Symbols:
FGF23

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Img

Fischer Scientific

7105379

Mouse Monoclonal Antibody...


Antigen:
FGF-23

Dilution:
ELISA, Functional

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
Q9GZV9

Gene ID (Entrez):
8074

Immunogen:
Recombinant human FGF23 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
FGF23/638

Applications:
ELISA, Functional Assay

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Angiogenesis, Cancer

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ADHR, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

Gene Symbols:
FGF23

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Img

Fischer Scientific

7105379

Mouse Monoclonal Antibody...


Antigen:
FGF-23

Dilution:
ELISA, Functional

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
Q9GZV9

Gene ID (Entrez):
8074

Immunogen:
Recombinant human FGF23 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
FGF23/638

Applications:
ELISA, Functional Assay

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Angiogenesis, Cancer

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ADHR, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

Gene Symbols:
FGF23

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.