7105379

FGF-23 Antibody (FGF23/638), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

FGF-23

Dilution

ELISA, Functional

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Accession No.

Q9GZV9

Gene ID (Entrez)

8074

Immunogen

Recombinant human FGF23 protein

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Clone

FGF23/638

Applications

ELISA, Functional Assay

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Angiogenesis, Cancer

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

ADHR, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

Gene Symbols

FGF23

Isotype

IgG1 κ

Purification Method

Protein A purified

Test Specificity

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

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Description

  • FGF-23 Monoclonal specifically detects FGF-23 in Human samples
  • It is validated for ELISA, Functional.

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Fischer Scientific

7105379

Mouse Monoclonal Antibody...


Antigen:
FGF-23

Dilution:
ELISA, Functional

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
Q9GZV9

Gene ID (Entrez):
8074

Immunogen:
Recombinant human FGF23 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
FGF23/638

Applications:
ELISA, Functional Assay

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Angiogenesis, Cancer

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ADHR, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

Gene Symbols:
FGF23

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Img

Fischer Scientific

7105380

Mouse Monoclonal Antibody has been ...


Antigen:
Fibronectin

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P02751

Gene ID (Entrez):
2335

Immunogen:
Human fibronectin purified from serum by affinity chromatography on gelatin-sepharose

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
HFN7.1

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CIGDKFZp686O13149, Cold-insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, fibronectin, fibronectin 1, FNFINC, FNZ, GFND2ED-B, LETSGFND, migration-stimulating factor, MSF

Gene Symbols:
FN1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
__

Img

Fischer Scientific

7105381

Mouse Monoclonal Antibody...


Antigen:
Fibronectin

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P02751

Gene ID (Entrez):
2335

Immunogen:
Human fibronectin purified from serum by affinity chromatography on gelatin-sepharose

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
SPM539

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CIGDKFZp686O13149, Cold-insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, fibronectin, fibronectin 1, FNFINC, FNZ, GFND2ED-B, LETSGFND, migration-stimulating factor, MSF

Gene Symbols:
FN1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Fibronectin is a dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.

Img

Fischer Scientific

7105383

Mouse Monoclonal Antibody...


Antigen:
Fibronectin

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Porcine

Gene Accession No.:
P02751

Gene ID (Entrez):
2335

Immunogen:
T-cell lymphoma biopsy

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
SPM246

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CIGDKFZp686O13149, Cold-insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, fibronectin, fibronectin 1, FNFINC, FNZ, GFND2ED-B, LETSGFND, migration-stimulating factor, MSF

Gene Symbols:
FN1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.