EPX Antibody (AHE-1), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
EPX
Dilution
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Formulation
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias
EC 1.11.1.7, eosinophil peroxidase, EPOEPER, EPPEC 1.11.1, EPX-PEN
Gene Symbols
EPX
Isotype
IgG1 κ
Purification Method
Protein A purified
Test Specificity
Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
Clone
AHE-1
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P11678
Gene ID (Entrez)
8288
Immunogen
Human eosinophils from a patient with hypereosinophilic syndrome
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Related Products
Description
- EPX Monoclonal specifically detects EPX in Human samples
- It is validated for ELISA.
Compare Similar Items
Show Difference
Antigen: EPX
Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: EC 1.11.1.7, eosinophil peroxidase, EPOEPER, EPPEC 1.11.1, EPX-PEN
Gene Symbols: EPX
Isotype: IgG1 κ
Purification Method: Protein A purified
Test Specificity: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
Clone: AHE-1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P11678
Gene ID (Entrez): 8288
Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen: ER alpha/NR3A1
Dilution: Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
Gene Symbols: ESR1
Isotype: IgG1 κ
Purification Method: Protein A purified
Test Specificity: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
Clone: SPM567
Applications: Western Blot, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P03372
Gene ID (Entrez): 2099
Immunogen: Recombinant human Estrogen Receptor alpha protein (aa2-185)
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen: GM-CSF
Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, molgramostin, sargramostim
Gene Symbols: CSF2
Isotype: IgG2a κ
Purification Method: Protein A purified
Test Specificity: Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.
Clone: SPM469
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human, Primate
Gene Accession No.: P04141
Gene ID (Entrez): 1437
Immunogen: Recombinant human GM-CSF protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
