7106027
CD8 Antibody (YTS 105.18) - Chimeric - Azide and BSA Free, Novus Biologicals™
Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD8 alpha
Dilution
Flow Cytometry 1:10 - 1:1000, Immunohistochemistry-Frozen 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Mouse
Gene Alias
CD8, CD8 antigen, alpha polypeptide (p32), CD8a antigen, CD8a molecule, Leu2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, RPA-T8, RPA-T8 antibody flow, RPA-T8 CD8, RPA-T8 Clone, RPA-T8 Flow, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Gene Symbols
CD8A
Isotype
IgG
Purification Method
Protein A or G purified
Test Specificity
Recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo.
Clone
YTS 105.18
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Blocking Assay, Immunofluorescence, CyTOF
Conjugate
Unconjugated
Host Species
Rabbit
Research Discipline
Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Formulation
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez)
925
Immunogen
Ly-2-transfected mouse L cells.
Primary or Secondary
Primary
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Description
- CD8 Monoclonal specifically detects CD8 in Mouse samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunofluorescence, CyTOF-ready, Block/Neutralize.
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Antigen: CD8 alpha
Dilution: Flow Cytometry 1:10 - 1:1000, Immunohistochemistry-Frozen 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: CD8, CD8 antigen, alpha polypeptide (p32), CD8a antigen, CD8a molecule, Leu2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, RPA-T8, RPA-T8 antibody flow, RPA-T8 CD8, RPA-T8 Clone, RPA-T8 Flow, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Gene Symbols: CD8A
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo.
Clone: YTS 105.18
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Blocking Assay, Immunofluorescence, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 925
Immunogen: Ly-2-transfected mouse L cells.
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen:
CD8 alpha
Dilution:
Flow Cytometry 1:10 - 1:1000, Immunohistochemistry-Frozen 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
CD8, CD8 antigen, alpha polypeptide (p32), CD8a antigen, CD8a molecule, Leu2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, RPA-T8, RPA-T8 antibody flow, RPA-T8 CD8, RPA-T8 Clone, RPA-T8 Flow, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Gene Symbols:
CD8A
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo.
Clone:
YTS 105.18
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Blocking Assay, Immunofluorescence, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Immunophenotyping, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
925
Immunogen:
Ly-2-transfected mouse L cells.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen: CD25/IL-2 R alpha
Dilution: Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols: IL2RA
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone: Daclizumab
Applications: Flow Cytometry, Blocking Assay, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 3559
Immunogen: Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary: Primary
Content And Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen:
CD25/IL-2 R alpha
Dilution:
Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone:
Daclizumab
Applications:
Flow Cytometry, Blocking Assay, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
3559
Immunogen:
Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen: CD25/IL-2 R alpha
Dilution: Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols: IL2RA
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone: Daclizumab
Applications: Flow Cytometry, Blocking Assay, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 3559
Immunogen: Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary: Primary
Content And Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen:
CD25/IL-2 R alpha
Dilution:
Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone:
Daclizumab
Applications:
Flow Cytometry, Blocking Assay, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
3559
Immunogen:
Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen: CD25/IL-2 R alpha
Dilution: Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols: IL2RA
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone: Basiliximab
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 3559
Immunogen: CD25
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen:
CD25/IL-2 R alpha
Dilution:
Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone:
Basiliximab
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
3559
Immunogen:
CD25
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.