SOX10 Mouse anti-Human, Mouse, Clone: SOX10/991, Novus Biologicals™
Mouse Monoclonal Antibody has been used in 1 publication
Manufacturer: Fischer Scientific
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Antigen
SOX10
Concentration
0.2 mg/mL
Applications
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse
Gene Alias
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of
Gene Symbols
SOX10
Isotype
IgG2b κ
Purification Method
Protein A or G purified
Test Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG -box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly exp
Clone
SOX10/991
Dilution
Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, SDS-Page, Protein Array 1:100-1:2000
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Formulation
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez)
6663
Immunogen
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietar
Primary or Secondary
Primary
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen
54 kDa
Related Products
Description
- SOX10 Monoclonal specifically detects SOX10 in Human, Mouse samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array, Flow (Intracellular).
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Antigen: SOX10
Concentration: 0.2 mg/mL
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Alias: MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of
Gene Symbols: SOX10
Isotype: IgG2b κ
Purification Method: Protein A or G purified
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG -box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly exp
Clone: SOX10/991
Dilution: Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, SDS-Page, Protein Array 1:100-1:2000
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez): 6663
Immunogen: Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietar
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 54 kDa
Antigen: __
Concentration: __
Applications: __
Conjugate: __
Host Species: __
Target Species: __
Gene Alias: __
Gene Symbols: __
Isotype: __
Purification Method: __
Test Specificity: __
Clone: __
Dilution: __
Classification: __
Form: __
Regulatory Status: __
Formulation: __
Gene ID (Entrez): __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Molecular Weight of Antigen: __
Antigen: 2A Peptide
Concentration: 1.0 mg/mL
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Non-species specific
Gene Alias: 2A cleavage peptide, 2A peptide, 2A peptide tag, 2A sequence, Anti- MDV 2A-peptide, anti-2A peptide, anti-2A sequence, anti-2A-like peptide, antibody for 2A-containing recombinant proteins, anti-P2A tagged proteins, anti-P2A peptide, anti-T2A tagged proteins, anti-T2A peptide, anti-Thosea asigna virus 2A, FMDV 2A-peptide peptide 2A sequences, self-cleaving'2A peptide2a pept, Thosea asigna virus 2A
Gene Symbols: __
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: This 2A peptide antibody is specific for T2A and P2A tagged proteins. Specificity to F2A and E2A proteins has not been tested.
Clone: 3H4
Dilution: Western Blot 1 ug/ml, Flow Cytometry reported by customer review, Immunocytochemistry/Immunofluorescence, Immunoprecipitation
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.02% Sodium Azide
Gene ID (Entrez): __
Immunogen: KLH-coupled synthetic peptide corresponding to 2A peptide of Thosea asigna virus (CGDVEENPG)
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: __
