7121231

MCM7 Mouse anti-Human, Clone: MCM7/1467, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

MCM7

Concentration

0.2 mg/mL

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers

Formulation

0mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez)

4176

Immunogen

Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen

88 kDa

Clone

MCM7/1467

Dilution

Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 3.6.4.12, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47

Gene Symbols

MCM7

Isotype

IgG2a κ

Purification Method

Protein A or G purified

Test Specificity

The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

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Description

  • Description MCM7 Monoclonal specifically detects MCM7 in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.

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Fischer Scientific

7121231

Mouse Monoclonal Antibody...


Antigen:
MCM7

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers

Formulation:
0mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
4176

Immunogen:
Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
88 kDa

Clone:
MCM7/1467

Dilution:
Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 3.6.4.12, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47

Gene Symbols:
MCM7

Isotype:
IgG2a κ

Purification Method:
Protein A or G purified

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

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7121233

Mouse Monoclonal Antibody...


Antigen:
MCM7

Concentration:
0.2 mg/mL

Applications:
__

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers

Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
4176

Immunogen:
Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
88 kDa

Clone:
MCM7/1469

Dilution:
Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 3.6.4.12, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47

Gene Symbols:
MCM7

Isotype:
IgG2b κ

Purification Method:
Protein A or G purified

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

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7121235

Mouse Monoclonal Antibody...


Antigen:
S100B

Concentration:
0.2 mg/mL

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Cytoskeleton Markers, Neuroscience, Stem Cells

Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
6285

Immunogen:
Recombinant full-length human S100B protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
13 kDa

Clone:
S100B/1012

Dilution:
Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.25-0.5 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Bovine

Gene Alias:
beta (neural), NEF, S100, S100 beta, S100 calcium binding protein B, S100 calcium-binding protein B, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, 10protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100beta

Gene Symbols:
S100B

Isotype:
IgG2a κ

Purification Method:
Protein A or G purified

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta -chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lip ocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumo

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7121235

Mouse Monoclonal Antibody...


Antigen:
S100B

Concentration:
0.2 mg/mL

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Cytoskeleton Markers, Neuroscience, Stem Cells

Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
6285

Immunogen:
Recombinant full-length human S100B protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
13 kDa

Clone:
S100B/1012

Dilution:
Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.25-0.5 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Bovine

Gene Alias:
beta (neural), NEF, S100, S100 beta, S100 calcium binding protein B, S100 calcium-binding protein B, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, 10protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100beta

Gene Symbols:
S100B

Isotype:
IgG2a κ

Purification Method:
Protein A or G purified

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta -chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lip ocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumo