7162610
CD49d (Integrin alpha 4) Monoclonal Antibody (R1-2), PE-Cyanine7, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD49d (Integrin alpha 4)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Alias
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Gene Symbols
ITGA4
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
ITGA4
Clone
R1-2
Applications
Flow Cytometry
Conjugate
PE-Cyanine7
Host Species
Rat
Target Species
Mouse
Gene Accession No.
Q00651
Gene ID (Entrez)
16401
Isotype
IgG2b κ
Purification Method
Affinity chromatography
Product Type
Antibody
Description
- Description: The R1-2 monoclonal antibody reacts with mouse CD49d, the 150 kDa integrin alpha4 subunit
- The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106)
- This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils
- CD49d also associates with integrin b7 and binds to the Mucosal vascular Addressin (MAdCAM-1)
- Applications Reported: This R1-2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This R1-2 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- Fixation: Samples can be stored in IC Fixation Buffer (Product No
- 00-8222-49) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No
- 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation
- The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
- Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
- Alpha4 chain associates with either beta1 or beta7 chain
- It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
- These ligands included Madcam, VCAM, and fibronectin
- Madcam is known as the principal ligand for integrin alpha4beta7
- Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Compare Similar Items
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Antigen: CD49d (Integrin alpha 4)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Alias: 269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Gene Symbols: ITGA4
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: ITGA4
Clone: R1-2
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Host Species: Rat
Target Species: Mouse
Gene Accession No.: Q00651
Gene ID (Entrez): 16401
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD49d (Integrin alpha 4)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Alias:
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Gene Symbols:
ITGA4
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
ITGA4
Clone:
R1-2
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
Q00651
Gene ID (Entrez):
16401
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD88 (C5aR1)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Alias: anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1
Gene Symbols: C5AR1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: C5AR1
Clone: 20/70
Applications: Flow Cytometry
Conjugate: Alexa Fluor 488
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P30993
Gene ID (Entrez): 12273
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD88 (C5aR1)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Alias:
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1
Gene Symbols:
C5AR1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
C5AR1
Clone:
20/70
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 488
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P30993
Gene ID (Entrez):
12273
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CK1 gamma-1
Concentration: __
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: __
Gene Alias: 9130020E21Rik; casein kinase 1 gamma 1; casein kinase 1, gamma 1; casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK I gamma1; CK1G1; CK1gamma1; CKI gamma 1; CKI gamma1; CK-I gamma1; CKI- gamma1; CKI gamma-1; CKI-gamma 1; CKI-gamma-1; CSNK1G1; KC1G1
Gene Symbols: Csnk1g1
Primary or Secondary: Primary
Content And Storage: -20°C or -80°C if preferred
Gene: Csnk1g1
Clone: __
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9HCP0
Gene ID (Entrez): 53944
Isotype: IgG
Purification Method: __
Product Type: Antibody
Antigen:
CK1 gamma-1
Concentration:
__
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
__
Gene Alias:
9130020E21Rik; casein kinase 1 gamma 1; casein kinase 1, gamma 1; casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK I gamma1; CK1G1; CK1gamma1; CKI gamma 1; CKI gamma1; CK-I gamma1; CKI- gamma1; CKI gamma-1; CKI-gamma 1; CKI-gamma-1; CSNK1G1; KC1G1
Gene Symbols:
Csnk1g1
Primary or Secondary:
Primary
Content And Storage:
-20°C or -80°C if preferred
Gene:
Csnk1g1
Clone:
__
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9HCP0
Gene ID (Entrez):
53944
Isotype:
IgG
Purification Method:
__
Product Type:
Antibody
Antigen: CX3CR1
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Gene Symbols: CX3CR1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: CX3CR1
Clone: 2A9-1
Applications: Flow Cytometry, Immunocytochemistry
Conjugate: Alexa Fluor 488
Host Species: Rat
Target Species: Human
Gene Accession No.: P49238
Gene ID (Entrez): 1524
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CX3CR1
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Gene Symbols:
CX3CR1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
CX3CR1
Clone:
2A9-1
Applications:
Flow Cytometry, Immunocytochemistry
Conjugate:
Alexa Fluor 488
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
P49238
Gene ID (Entrez):
1524
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody