7162620

CD88 (C5aR1) Monoclonal Antibody (20/70), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD88 (C5aR1)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide, pH 7.2

Gene Alias

anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1

Gene Symbols

C5AR1

Isotype

IgG2b κ

Purification Method

Affinity chromatography

Product Type

Antibody

Clone

20/70

Applications

Flow Cytometry

Conjugate

Alexa Fluor 488

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P30993

Gene ID (Entrez)

12273

Immunogen

RBL-2H3 transfected cells expressing murine C5aR

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

C5AR1

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Description

  • Description: This 20/70 monoclonal antibody recognizes mouse CD88 also known as C5aR1
  • CD88 is a complement receptor widely expressed on cells of the myeloid lineage
  • Clone 20/70 has been reported to block the binding of C5a to murine CD88
  • Applications Reported: This 20/70 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 20/70 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
  • This may be used at less than or equal to 1.0 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
  • C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
  • CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
  • Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
  • CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
  • Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.

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7162620

Rat Monoclonal Antibody...


Antigen:
CD88 (C5aR1)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Alias:
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1

Gene Symbols:
C5AR1

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
20/70

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 488

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P30993

Gene ID (Entrez):
12273

Immunogen:
RBL-2H3 transfected cells expressing murine C5aR

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
C5AR1

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Rabbit Polyclonal Antibody...


Antigen:
CK1 gamma-1

Concentration:
__

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
9130020E21Rik; casein kinase 1 gamma 1; casein kinase 1, gamma 1; casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK I gamma1; CK1G1; CK1gamma1; CKI gamma 1; CKI gamma1; CK-I gamma1; CKI- gamma1; CKI gamma-1; CKI-gamma 1; CKI-gamma-1; CSNK1G1; KC1G1

Gene Symbols:
Csnk1g1

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Clone:
__

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9HCP0

Gene ID (Entrez):
53944

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
-20°C or -80°C if preferred

Gene:
Csnk1g1

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Antigen:
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Concentration:
5 μL/Test

Classification:
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Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28

Gene Symbols:
CX3CR1

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
2A9-1

Applications:
Flow Cytometry, Immunocytochemistry

Conjugate:
Alexa Fluor 488

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P49238

Gene ID (Entrez):
1524

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CX3CR1

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Antigen:
E4BP4 (NFIL3)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
AV225605, E4 promoter binding-protein 4, E4 promoter-binding protein 4, E4BP4, Embryo implantation-related NFIL3/E4BP4-like transcription factor, IL3BP1, Interleukin-3 promoter transcriptional activator, interleukin-3-binding protein 1, NF IL3A, NFIL3, NFIL3A, NF-IL3A, nuclear factor interleukin 3 regulated protein, nuclear factor interleukin-3-regulated protein, nuclear factor, interleukin 3 regulated, nuclear factor, interleukin 3, regulated, OTTHUMP00000021633, transcriptional activator NF-IL3A

Gene Symbols:
NFIL3

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
MABA223

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 647

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q16649

Gene ID (Entrez):
4783

Immunogen:
21H2-hNFIL3 (aa 163-462)

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
NFIL3