7162625
CX3CR1 Monoclonal Antibody (2A9-1), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CX3CR1
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias
Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Gene Symbols
CX3CR1
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
CX3CR1
Clone
2A9-1
Applications
Flow Cytometry, Immunocytochemistry
Conjugate
Alexa Fluor 488
Host Species
Rat
Target Species
Human
Gene Accession No.
P49238
Gene ID (Entrez)
1524
Isotype
IgG2b κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family
- CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g
- CD8+, CD4+, and gamma/delta), and monocytes
- In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia
- Little to no CX3CR1 surface expression can be detected on B cells and granulocytes
- Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes
- The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B
- Applications Reported: This 2A9-1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 2A9-1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection
- The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively
- The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1
- Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine
- CX3CR1 mediates leukocyte migration an d adhesion
- CX3CR1 is expressed in a variety of human tissues and cell lines.
Compare Similar Items
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Antigen: CX3CR1
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Gene Symbols: CX3CR1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: CX3CR1
Clone: 2A9-1
Applications: Flow Cytometry, Immunocytochemistry
Conjugate: Alexa Fluor 488
Host Species: Rat
Target Species: Human
Gene Accession No.: P49238
Gene ID (Entrez): 1524
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CX3CR1
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Gene Symbols:
CX3CR1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
CX3CR1
Clone:
2A9-1
Applications:
Flow Cytometry, Immunocytochemistry
Conjugate:
Alexa Fluor 488
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
P49238
Gene ID (Entrez):
1524
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: E4BP4 (NFIL3)
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias: AV225605, E4 promoter binding-protein 4, E4 promoter-binding protein 4, E4BP4, Embryo implantation-related NFIL3/E4BP4-like transcription factor, IL3BP1, Interleukin-3 promoter transcriptional activator, interleukin-3-binding protein 1, NF IL3A, NFIL3, NFIL3A, NF-IL3A, nuclear factor interleukin 3 regulated protein, nuclear factor interleukin-3-regulated protein, nuclear factor, interleukin 3 regulated, nuclear factor, interleukin 3, regulated, OTTHUMP00000021633, transcriptional activator NF-IL3A
Gene Symbols: NFIL3
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: NFIL3
Clone: MABA223
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q16649
Gene ID (Entrez): 4783
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
E4BP4 (NFIL3)
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
AV225605, E4 promoter binding-protein 4, E4 promoter-binding protein 4, E4BP4, Embryo implantation-related NFIL3/E4BP4-like transcription factor, IL3BP1, Interleukin-3 promoter transcriptional activator, interleukin-3-binding protein 1, NF IL3A, NFIL3, NFIL3A, NF-IL3A, nuclear factor interleukin 3 regulated protein, nuclear factor interleukin-3-regulated protein, nuclear factor, interleukin 3 regulated, nuclear factor, interleukin 3, regulated, OTTHUMP00000021633, transcriptional activator NF-IL3A
Gene Symbols:
NFIL3
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
NFIL3
Clone:
MABA223
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q16649
Gene ID (Entrez):
4783
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: Glucocorticoid receptor (NR3C1)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Alias: cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Gene Symbols: Nr3c1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Nr3c1
Clone: BuGR2
Applications: Flow Cytometry
Conjugate: Alexa Fluor 488
Host Species: Mouse
Target Species: Mouse
Gene Accession No.: P06537
Gene ID (Entrez): 14815
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
Glucocorticoid receptor (NR3C1)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Alias:
cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Gene Symbols:
Nr3c1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Nr3c1
Clone:
BuGR2
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 488
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
P06537
Gene ID (Entrez):
14815
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: Glucocorticoid receptor (NR3C1)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Alias: cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Gene Symbols: Nr3c1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Nr3c1
Clone: BuGR2
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Host Species: Mouse
Target Species: Mouse
Gene Accession No.: P06537
Gene ID (Entrez): 14815
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
Glucocorticoid receptor (NR3C1)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Alias:
cytosolic/nuclear receptor, fb13f09, GCCR, Gcr, GCRST, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, glucocorticoid receptor 1, glucocorticoid receptor alpha, GR, gr alpha, GR Kit, Grl, Grl1, Grl-1, Nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), OTTHUMP00000222854, OTTHUMP00000222858, utouto, utut, wu:fb13f09, zgc:113038
Gene Symbols:
Nr3c1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Nr3c1
Clone:
BuGR2
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
P06537
Gene ID (Entrez):
14815
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody