7182738
L-Selectin/CD62L, Rabbit anti-Mouse, Clone: MEL-14, Novus Biologicals™
Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
L-Selectin/CD62L
Concentration
1 mg/mL
Applications
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay
Conjugate
Unconjugated
Host Species
Rabbit
Research Discipline
Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation
PBS
Gene ID (Entrez)
6402
Immunogen
C3H/eb mouse B lymphoma 38C-13.
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone
MEL-14
Dilution
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Block/Neutralize
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Mouse
Gene Alias
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols
SELL
Isotype
IgG κ
Purification Method
Protein A purified
Test Specificity
This antibody binds to mouse L-Selectin/CD62L the mouse peripheral lymph node homing receptor, which is a lectin-like cell surface protein rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.
Related Products
Description
- Description L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Mouse samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Block/Neutralize.
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Antigen: L-Selectin/CD62L
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation: PBS
Gene ID (Entrez): 6402
Immunogen: C3H/eb mouse B lymphoma 38C-13.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: MEL-14
Dilution: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols: SELL
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: This antibody binds to mouse L-Selectin/CD62L the mouse peripheral lymph node homing receptor, which is a lectin-like cell surface protein rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.
Antigen:
L-Selectin/CD62L
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation:
PBS
Gene ID (Entrez):
6402
Immunogen:
C3H/eb mouse B lymphoma 38C-13.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
MEL-14
Dilution:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols:
SELL
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
This antibody binds to mouse L-Selectin/CD62L the mouse peripheral lymph node homing receptor, which is a lectin-like cell surface protein rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.
Antigen: L-Selectin/CD62L
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation: PBS
Gene ID (Entrez): 6402
Immunogen: This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: DREG-56
Dilution: Western Blot, Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Bovine, Chimpanzee
Gene Alias: CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols: SELL
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: This antibody is specific for human L-Selectin/CD62L, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.
Antigen:
L-Selectin/CD62L
Concentration:
1 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation:
PBS
Gene ID (Entrez):
6402
Immunogen:
This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
DREG-56
Dilution:
Western Blot, Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Bovine, Chimpanzee
Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols:
SELL
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
This antibody is specific for human L-Selectin/CD62L, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.
Antigen: Endoglin/CD105
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Formulation: PBS
Gene ID (Entrez): 2022
Immunogen: MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: MJ7/18
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
Gene Symbols: ENG
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
Antigen:
Endoglin/CD105
Concentration:
1 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Formulation:
PBS
Gene ID (Entrez):
2022
Immunogen:
MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
MJ7/18
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
Gene Symbols:
ENG
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
Antigen: Integrin beta 7
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Signal Transduction
Formulation: PBS
Gene ID (Entrez): 3695
Immunogen: FIB27 was prepared by immunizing rats with TK1 cells.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: FIB27
Dilution: Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Alias: Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols: ITGB7
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
Antigen:
Integrin beta 7
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Signal Transduction
Formulation:
PBS
Gene ID (Entrez):
3695
Immunogen:
FIB27 was prepared by immunizing rats with TK1 cells.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
FIB27
Dilution:
Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Alias:
Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols:
ITGB7
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.