7182739
L-Selectin/CD62L, Rabbit anti-Human,Bovine,Chimpanzee, Clone: DREG-56, Novus Biologicals™
Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
L-Selectin/CD62L
Concentration
1 mg/mL
Applications
Western Blot, Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate
Unconjugated
Host Species
Rabbit
Research Discipline
Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation
PBS
Gene ID (Entrez)
6402
Immunogen
This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone
DREG-56
Dilution
Western Blot, Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human, Bovine, Chimpanzee
Gene Alias
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols
SELL
Isotype
IgG κ
Purification Method
Protein A purified
Test Specificity
This antibody is specific for human L-Selectin/CD62L, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.
Related Products
Description
- Description L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Human, Bovine, Chimpanzee samples
- It is validated for Western Blot, Flow Cytometry, Immunoprecipitation, Block/Neutralize.
Compare Similar Items
Show Difference
Antigen: L-Selectin/CD62L
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation: PBS
Gene ID (Entrez): 6402
Immunogen: This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: DREG-56
Dilution: Western Blot, Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Bovine, Chimpanzee
Gene Alias: CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols: SELL
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: This antibody is specific for human L-Selectin/CD62L, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.
Antigen:
L-Selectin/CD62L
Concentration:
1 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Formulation:
PBS
Gene ID (Entrez):
6402
Immunogen:
This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
DREG-56
Dilution:
Western Blot, Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Bovine, Chimpanzee
Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Gene Symbols:
SELL
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
This antibody is specific for human L-Selectin/CD62L, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.
Antigen: Endoglin/CD105
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Formulation: PBS
Gene ID (Entrez): 2022
Immunogen: MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: MJ7/18
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
Gene Symbols: ENG
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
Antigen:
Endoglin/CD105
Concentration:
1 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Formulation:
PBS
Gene ID (Entrez):
2022
Immunogen:
MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
MJ7/18
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
Gene Symbols:
ENG
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
Antigen: Integrin beta 7
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Signal Transduction
Formulation: PBS
Gene ID (Entrez): 3695
Immunogen: FIB27 was prepared by immunizing rats with TK1 cells.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: FIB27
Dilution: Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Alias: Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols: ITGB7
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
Antigen:
Integrin beta 7
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Signal Transduction
Formulation:
PBS
Gene ID (Entrez):
3695
Immunogen:
FIB27 was prepared by immunizing rats with TK1 cells.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
FIB27
Dilution:
Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Alias:
Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols:
ITGB7
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
Antigen: Integrin beta 7
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Signal Transduction
Formulation: PBS
Gene ID (Entrez): 3695
Immunogen: FIB27 was prepared by immunizing rats with TK1 cells.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone: FIB27
Dilution: Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Alias: Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols: ITGB7
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
Antigen:
Integrin beta 7
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunoprecipitation, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Signal Transduction
Formulation:
PBS
Gene ID (Entrez):
3695
Immunogen:
FIB27 was prepared by immunizing rats with TK1 cells.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone:
FIB27
Dilution:
Flow Cytometry, Immunoprecipitation, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Alias:
Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols:
ITGB7
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.