7188381
IRF-3 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IRF-3
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q14653
Gene ID (Entrez)
3661
Immunogen
This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Primary or Secondary
Primary
Product Type
Antibody
Concentration
Conc. Not Determined
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Gene Symbols
IRF3
Isotype
IgG
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
IRF3
Related Products
Description
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
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Antigen: IRF-3
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q14653
Gene ID (Entrez): 3661
Immunogen: This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Gene Symbols: IRF3
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: IRF3
Antigen:
IRF-3
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q14653
Gene ID (Entrez):
3661
Immunogen:
This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Gene Symbols:
IRF3
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
IRF3
Antigen: GATA-6
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q92908
Gene ID (Entrez): 2627
Immunogen: This GATA-6 antibody was raised against a peptide within the N-terminus of human GATA-6.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: AA410133; ASD9; AVSD5; BOS_22226; DNA-binding protein GATA-GT2; GATA binding protein 6; Gata6; GATA-6; GATA-binding factor 6; GATA-binding protein 6; LOW QUALITY PROTEIN: transcription factor GATA-6; transcription factor GATA6; Transcription factor GATA-6
Gene Symbols: GATA6
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: GATA6
Antigen:
GATA-6
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q92908
Gene ID (Entrez):
2627
Immunogen:
This GATA-6 antibody was raised against a peptide within the N-terminus of human GATA-6.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
AA410133; ASD9; AVSD5; BOS_22226; DNA-binding protein GATA-GT2; GATA binding protein 6; Gata6; GATA-6; GATA-binding factor 6; GATA-binding protein 6; LOW QUALITY PROTEIN: transcription factor GATA-6; transcription factor GATA6; Transcription factor GATA-6
Gene Symbols:
GATA6
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
GATA6
Antigen: LexA DNA-binding Domain
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Yeast
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: This LexA DNA-binding Domain antibody was raised against recombinant protein corresponding to full-lengthE. coliLexA.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: __
Gene Symbols: __
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: __
Antigen:
LexA DNA-binding Domain
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Yeast
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
This LexA DNA-binding Domain antibody was raised against recombinant protein corresponding to full-lengthE. coliLexA.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
__
Gene Symbols:
__
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
__
Antigen: JunB
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P17275
Gene ID (Entrez): 3726
Immunogen: This JunB antibody was raised against a synthetic peptide corresponding to amino acids 28-42 of human JunB.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: activator protein 1; AP-1; Jun B; jun B proto-oncogene; JUNB; Jun-b; Jun-B oncogene; JunB proto-oncogene, AP-1 transcription factor subunit; MyD21; Oncogene Jun-B; Transcription factor jun-B
Gene Symbols: Junb
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Junb
Antigen:
JunB
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P17275
Gene ID (Entrez):
3726
Immunogen:
This JunB antibody was raised against a synthetic peptide corresponding to amino acids 28-42 of human JunB.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
activator protein 1; AP-1; Jun B; jun B proto-oncogene; JUNB; Jun-b; Jun-B oncogene; JunB proto-oncogene, AP-1 transcription factor subunit; MyD21; Oncogene Jun-B; Transcription factor jun-B
Gene Symbols:
Junb
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Junb