7188552
Progerin Monoclonal Antibody (13A4), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Progerin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32
Gene Symbols
LMNA
Isotype
IgG1 κ
Purification Method
Protein G
Product Type
Antibody
Clone
13A4
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P02545
Gene ID (Entrez)
4000
Immunogen
This Progerin antibody was raised against a peptide corresponding to amino acids 604-611 of human Progerin.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
LMNA
Related Products
Description
- Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome
- Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin-A/C
- This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acid internal deletion within the C-terminal domain of the protein
- Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of the LMNA gene.
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Antigen: Progerin
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: 70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32
Gene Symbols: LMNA
Isotype: IgG1 κ
Purification Method: Protein G
Product Type: Antibody
Clone: 13A4
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P02545
Gene ID (Entrez): 4000
Immunogen: This Progerin antibody was raised against a peptide corresponding to amino acids 604-611 of human Progerin.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: LMNA
Antigen:
Progerin
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32
Gene Symbols:
LMNA
Isotype:
IgG1 κ
Purification Method:
Protein G
Product Type:
Antibody
Clone:
13A4
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P02545
Gene ID (Entrez):
4000
Immunogen:
This Progerin antibody was raised against a peptide corresponding to amino acids 604-611 of human Progerin.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
LMNA
Antigen: OGA/O-GlcNAcase
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 2810009A20Rik; 4833427O07Rik; 5830447M11Rik; AA408215; Beta-hexosaminidase; Beta-N-acetylglucosaminidase; Beta-N-acetylhexosaminidase; Bifunctional protein NCOAT; HEXC; Hy5; hyaluronidase in meningioma; Kiaa0679; Mea5; meningioma expressed antigen 5 (hyaluronidase); Meningioma-expressed antigen 5; MGEA5; mKIAA0679; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; NCOAT; Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; OGA; O-GLCNACASE; Protein O-GlcNAcase
Gene Symbols: Oga
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O60502
Gene ID (Entrez): 10724
Immunogen: This antibody was raised against a peptide within the N-terminal region of human OGA/ O-GlcNAcase.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Oga
Antigen:
OGA/O-GlcNAcase
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
2810009A20Rik; 4833427O07Rik; 5830447M11Rik; AA408215; Beta-hexosaminidase; Beta-N-acetylglucosaminidase; Beta-N-acetylhexosaminidase; Bifunctional protein NCOAT; HEXC; Hy5; hyaluronidase in meningioma; Kiaa0679; Mea5; meningioma expressed antigen 5 (hyaluronidase); Meningioma-expressed antigen 5; MGEA5; mKIAA0679; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; NCOAT; Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; OGA; O-GLCNACASE; Protein O-GlcNAcase
Gene Symbols:
Oga
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O60502
Gene ID (Entrez):
10724
Immunogen:
This antibody was raised against a peptide within the N-terminal region of human OGA/ O-GlcNAcase.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Oga
Antigen: CTCF
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: 11 zinc finger transcriptional repressor; 11-zinc finger protein; AW108038; BOS_17095; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein); CTCF; ctcf protein; CTCFL paralog; im:7152666; MRD21; OTTHUMP00000197610; Transcriptional repressor CTCF; Unknown (protein for IMAGE:8125283)
Gene Symbols: CTCF
Isotype: IgG
Purification Method: Protein A
Product Type: Antibody
Clone: __
Applications: ChIP sequencing (ChIP-seq), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P49711
Gene ID (Entrez): 10664
Immunogen: This antibody was raised against a peptide within human CTCF.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: CTCF
Antigen:
CTCF
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
11 zinc finger transcriptional repressor; 11-zinc finger protein; AW108038; BOS_17095; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein); CTCF; ctcf protein; CTCFL paralog; im:7152666; MRD21; OTTHUMP00000197610; Transcriptional repressor CTCF; Unknown (protein for IMAGE:8125283)
Gene Symbols:
CTCF
Isotype:
IgG
Purification Method:
Protein A
Product Type:
Antibody
Clone:
__
Applications:
ChIP sequencing (ChIP-seq), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P49711
Gene ID (Entrez):
10664
Immunogen:
This antibody was raised against a peptide within human CTCF.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
CTCF
Antigen: JMJD2B / KDM4B
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: 4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; Jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; Lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B
Gene Symbols: KDM4B
Isotype: IgG2a
Purification Method: Protein A
Product Type: Antibody
Clone: __
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: O94953
Gene ID (Entrez): 23030
Immunogen: This antibody was raised against full-length recombinant human lysine-specific demethylase 4B (kDM4B) protein.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: KDM4B
Antigen:
JMJD2B / KDM4B
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; Jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; Lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B
Gene Symbols:
KDM4B
Isotype:
IgG2a
Purification Method:
Protein A
Product Type:
Antibody
Clone:
__
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
O94953
Gene ID (Entrez):
23030
Immunogen:
This antibody was raised against full-length recombinant human lysine-specific demethylase 4B (kDM4B) protein.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
KDM4B