7188635

Lamin A, mature Monoclonal Antibody (4A4), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Lamin A, mature

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

70 kDa lamin; BOS_2775; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A; lamin A/C; lamin A/C-like 1; lamin C; lamin C2; Lamin-A/C; LDP1; LFP; LGMD1B; Lmn1; LMNA; LMNC; LMNL1; OTTHUMP00000015843; OTTHUMP00000015846; OTTHUMP00000015847; Prelamin-A/C; PRO1; Renal carcinoma antigen NY-REN-32

Gene Symbols

LMNA

Isotype

IgG1

Purification Method

Protein G

Product Type

Antibody

Clone

4A4

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P02545

Gene ID (Entrez)

4000

Immunogen

This Lamin A, mature antibody was raised against a peptide within the C-terminus of mature human Lamin A.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

LMNA

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Description

  • Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane
  • Two main subtypes of nuclear lamins can be distinguished, i.e
  • A-type lamins and B-type lamins
  • The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e
  • lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e
  • lamin B1 and lamin B2
  • Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy
  • In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.

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Fischer Scientific

7188635

Mouse Monoclonal Antibody...


Antigen:
Lamin A, mature

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
70 kDa lamin; BOS_2775; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A; lamin A/C; lamin A/C-like 1; lamin C; lamin C2; Lamin-A/C; LDP1; LFP; LGMD1B; Lmn1; LMNA; LMNC; LMNL1; OTTHUMP00000015843; OTTHUMP00000015846; OTTHUMP00000015847; Prelamin-A/C; PRO1; Renal carcinoma antigen NY-REN-32

Gene Symbols:
LMNA

Isotype:
IgG1

Purification Method:
Protein G

Product Type:
Antibody

Clone:
4A4

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P02545

Gene ID (Entrez):
4000

Immunogen:
This Lamin A, mature antibody was raised against a peptide within the C-terminus of mature human Lamin A.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
LMNA

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Fischer Scientific

7188638

Mouse Monoclonal Antibody...


Antigen:
Prox1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
A230003G05Rik; Homeobox prospero-like protein PROX1; prospero homeobox 1; Prospero homeobox protein 1; prospero-related homeobox 1; PROX1; PROX-1

Gene Symbols:
Prox1

Isotype:
IgG1

Purification Method:
Protein G

Product Type:
Antibody

Clone:
5G10

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q92786

Gene ID (Entrez):
5629

Immunogen:
This Prox1 antibody was raised against a recombinant protein corresponding to amino acids 547-737 of human Prox1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Prox1

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7188640

Rabbit Polyclonal Antibody...


Antigen:
FOXL2

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
AU045128; Blepharophimosis; BOS_1244; BPES; BPES1; epicanthus inversus; forkhead box L2; Forkhead box protein L2; forkhead transcription factor FOXL2; forkhead transcription factor L2; Foxl2; LUSTR2; MGC14393; Pfrk; P-Frk; PINTO; Pituitary forkhead factor; POF3; putative transcription factor foxl2

Gene Symbols:
FOXL2

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Clone:
__

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P58012

Gene ID (Entrez):
668

Immunogen:
This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
FOXL2

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7188642

Rabbit Polyclonal Antibody...


Antigen:
Histone H2BK16ac

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K16; Acetyl-Histone H2B Lys16; AV127319; dJ193B12.2; dJ221C16.3; dJ221C16.8; GL105; H2B; H2b 613; H2B GL105; H2B histone family, member A; H2B histone family, member D; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member S; H2B histone family, member T; H2B K; H2B.1; H2B.1A; H2B.2; H2B/a; H2B/d; H2B/g; H2B/h; H2B/I; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/s; H2B/t; H2b-613; H2BC10; H2BC4; H2BC6; H2BC7; H2bc8; H2BFA; H2BFAiii; H2BFD; H2BFG; H2BFH; H2BFK; H2BFL; H2BFN; H2BFO; H2BFQ; H2bfs; H2BFT; H2BGL105; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRIP1; Hist1h2ba; Hist1h2bc; Hist1h2be; HIST1H2BF; Hist1h2bg; HIST1H2BI; Hist1h2bk; HIST1H2BN; HIST1H2BO; HIST1H3I; HIST2H2BC; HIST2H2BD; Hist2h2be; HIST2H2BF; histone 1, H2ba; histone 1, H2bc; histone 1, H2bg; histone 1, H2bi; histone 1, H2bk; histone 1,

Gene Symbols:
H2BC10, H2BC12, H2BC15, H2BC17, H2BC18, H2BC19P, H2BC20P, H2BC21, H2BC4, H2BC8

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Clone:
__

Applications:
ChIP Assay, Dot Blot, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O60814, P23527, P62807, Q16778, Q5QNW6, Q6DN03, Q6DRA6, Q99877

Gene ID (Entrez):
337873, 337874, 440689, 8339, 8341, 8346, 8347, 8348, 8349, 85236

Immunogen:
This Histone H2B acetyl Lys16 antibody was raised against a peptide including acetyl-lysine 16 of human histone H2B.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H2BC12