Phospho-RNA pol II CTD (Ser2, Ser5) Monoclonal Antibody (1A12G10), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospho-RNA pol II CTD (Ser2, Ser5)
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept
Gene Symbols
POLA1, POLR2A
Isotype
IgG1 κ
Purification Method
Protein A
Product Type
Antibody
Clone
1A12G10
Applications
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P09884, P24928
Gene ID (Entrez)
5422, 5430
Immunogen
This antibody was raised against a synthetic peptide containing phospho-serine 2 and phospho-serine 5 of the CTD of human RNA Polymerase II.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
POLR2A
Related Products
Description
- RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs
- POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II
- The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS
- Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle
- Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.
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Antigen: Phospho-RNA pol II CTD (Ser2, Ser5)
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept
Gene Symbols: POLA1, POLR2A
Isotype: IgG1 κ
Purification Method: Protein A
Product Type: Antibody
Clone: 1A12G10
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P09884, P24928
Gene ID (Entrez): 5422, 5430
Immunogen: This antibody was raised against a synthetic peptide containing phospho-serine 2 and phospho-serine 5 of the CTD of human RNA Polymerase II.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: POLR2A
Antigen: Phospho-MeCP2 (Ser80)
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: 1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; Methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
Gene Symbols: Mecp2
Isotype: IgG
Purification Method: __
Product Type: Antibody
Clone: __
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Rat
Gene Accession No.: P51608, Q00566
Gene ID (Entrez): 29386, 4204
Immunogen: This MeCP2 phospho Ser80 antibody was raised against a peptide containing phospho Ser80 of mouse MeCP2.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Mecp2
Antigen: Phospho-MeCP2 (Ser80)
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: 1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; Methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
Gene Symbols: Mecp2
Isotype: IgG
Purification Method: __
Product Type: Antibody
Clone: __
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Rat
Gene Accession No.: P51608, Q00566
Gene ID (Entrez): 29386, 4204
Immunogen: This MeCP2 phospho Ser80 antibody was raised against a peptide containing phospho Ser80 of mouse MeCP2.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Mecp2
