7188965

Phospho-RNA pol II CTD (Ser5) Monoclonal Antibody (3E8), Active Motif™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-RNA pol II CTD (Ser5)

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept

Gene Symbols

POLA1, POLR2A

Isotype

IgG2a

Purification Method

Protein G

Product Type

Antibody

Clone

3E8

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Rat

Target Species

Human

Gene Accession No.

P09884, P24928

Gene ID (Entrez)

5422, 5430

Immunogen

This RNA pol II CTD phospho Ser5 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 5.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

POLR2A

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Description

  • RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs
  • POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II
  • The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS
  • Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle
  • Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.

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7188965

Rat Monoclonal Antibody...


Antigen:
Phospho-RNA pol II CTD (Ser5)

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept

Gene Symbols:
POLA1, POLR2A

Isotype:
IgG2a

Purification Method:
Protein G

Product Type:
Antibody

Clone:
3E8

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P09884, P24928

Gene ID (Entrez):
5422, 5430

Immunogen:
This RNA pol II CTD phospho Ser5 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 5.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLR2A

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7188966

Mouse Monoclonal Antibody...


Antigen:
BubR1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; BUB1B; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1

Gene Symbols:
BUB1B

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Clone:
8G1

Applications:
Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
O60566, Q9Z1S0

Gene ID (Entrez):
12236, 701

Immunogen:
This BubR1 antibody was raised against recombinant protein corresponding to amino acids 1-350 of human BubR1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
BUB1B

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Mouse Monoclonal Antibody...


Antigen:
Bcl6

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; BCL6; Bcl-6; BCL6 transcription repressor; BCL6A; BOS_960; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; lymphoma-associated zinc finger gene on chromosome 3; Protein LAZ-3; ZBTB27; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51; zinc finger transcription factor BCL6S; ZNF51

Gene Symbols:
BCL6

Isotype:
IgG1

Purification Method:
Protein G

Product Type:
Antibody

Clone:
IG191E

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P41182

Gene ID (Entrez):
604

Immunogen:
This Bcl6 antibody was raised against a full-length protein corresponding to human Bcl6.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
BCL6

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Rabbit Polyclonal Antibody...


Antigen:
NF-1A

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; KIAA1439; MRSHSS; NF1A; NF1-A; NF1-B; NF1-C; NF1-X; NF1-X1 protein; NFI; NF-I/A; NF-I/B; NF-I/C; NF-I/X; NFIA; NFI-A; NFIB; NFI-B; NFIC; NFI-C; Nfix; NFI-X; Nuclear factor 1 X-type; Nuclear factor 1/A; Nuclear factor 1/B; Nuclear factor 1/C; nuclear factor 1/X; nuclear factor I X; Nuclear factor I/A; Nuclear factor I/B; Nuclear factor I/C; Nuclear factor I/X; nuclear factor I/X (CCAAT-binding transcription factor); SOTOS2; TGGCA-binding protein

Gene Symbols:
NFIX

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Clone:
__

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q14938

Gene ID (Entrez):
4784

Immunogen:
This NF-1A antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 478-492 of human NF-1A.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
NFIX