7188943
5-Methylcytosine (5-mC) Monoclonal Antibody (A1), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
5-Methylcytosine (5-mC)
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen
This 5-Methylcytosine (5-mC) antibody was raised against 5-Methyl-cytidine conjugated to kLH and recognizes 5-Methylcytosine.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Clone
A1
Applications
ChIP sequencing (ChIP-seq), Dot Blot, Immunoprecipitation
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Alias
5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Related Products
Description
- Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription
- It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated
- An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes
- Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
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Antigen: 5-Methylcytosine (5-mC)
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen: This 5-Methylcytosine (5-mC) antibody was raised against 5-Methyl-cytidine conjugated to kLH and recognizes 5-Methylcytosine.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Clone: A1
Applications: ChIP sequencing (ChIP-seq), Dot Blot, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Alias: 5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Isotype: IgG1
Purification Method: Protein A
Product Type: Antibody
Antigen:
5-Methylcytosine (5-mC)
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen:
This 5-Methylcytosine (5-mC) antibody was raised against 5-Methyl-cytidine conjugated to kLH and recognizes 5-Methylcytosine.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Clone:
A1
Applications:
ChIP sequencing (ChIP-seq), Dot Blot, Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Alias:
5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Isotype:
IgG1
Purification Method:
Protein A
Product Type:
Antibody
Antigen: FOXP1
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen: This FOXP1 antibody was raised against a recombinant protein corresponding to amino acids 495-578 of mouse FOXP1. This antibody detects three isoforms.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Clone: 1G1
Applications: ChIP Assay, Gel Shift, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Mouse
Gene Alias: 12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; fork head-related protein like B; forkhead box P1; Forkhead box protein P1; Forkhead-related transcription factor 1; FOXP1; glutamine-rich factor 1; hFKH1B; HSPC215; Mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1
Isotype: IgG1
Purification Method: Protein A
Product Type: Antibody
Antigen:
FOXP1
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen:
This FOXP1 antibody was raised against a recombinant protein corresponding to amino acids 495-578 of mouse FOXP1. This antibody detects three isoforms.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Clone:
1G1
Applications:
ChIP Assay, Gel Shift, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Mouse
Gene Alias:
12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; fork head-related protein like B; forkhead box P1; Forkhead box protein P1; Forkhead-related transcription factor 1; FOXP1; glutamine-rich factor 1; hFKH1B; HSPC215; Mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1
Isotype:
IgG1
Purification Method:
Protein A
Product Type:
Antibody
Antigen: SALL4
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Immunogen: This SALL4 antibody was raised against a synthetic peptide derived from the N-terminus of human SALL4.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Clone: __
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Alias: 5730441M18Rik; AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; CH242-152A8.2; dJ1112F19.1; DRRS; HSAL4; SALL4; sal-like 4; sal-like 4 (Drosophila); Sal-like protein 4; spalt like transcription factor 4; spalt-like transcription factor 4; Tex20; Zinc finger protein 797; Zinc finger protein SALL4; ZNF797
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
SALL4
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Immunogen:
This SALL4 antibody was raised against a synthetic peptide derived from the N-terminus of human SALL4.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Clone:
__
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Alias:
5730441M18Rik; AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; CH242-152A8.2; dJ1112F19.1; DRRS; HSAL4; SALL4; sal-like 4; sal-like 4 (Drosophila); Sal-like protein 4; spalt like transcription factor 4; spalt-like transcription factor 4; Tex20; Zinc finger protein 797; Zinc finger protein SALL4; ZNF797
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: FTO
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen: This antibody was raised against a peptide within the N-terminal region of human FTO.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Clone: __
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Alias: AlkB homolog 9; ALKBH9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; Fat mass and obesity-associated protein; fatso; FTO; GDFD; Kiaa1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
FTO
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen:
This antibody was raised against a peptide within the N-terminal region of human FTO.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Clone:
__
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
AlkB homolog 9; ALKBH9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; Fat mass and obesity-associated protein; fatso; FTO; GDFD; Kiaa1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody