7190539
Deoxyribonuclease I Polyclonal Antibody, HRP, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Deoxyribonuclease I
Applications
ELISA, Immunoprecipitation, Western Blot
Conjugate
HRP
Host Species
Rabbit
Target Species
Bovine
Gene Accession No.
P00639
Gene ID (Entrez)
282217
Immunogen
Deoxyribonuclease I [Bovine Pancreas]
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene
DNASE1
Concentration
1 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias
AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I
Gene Symbols
DNASE1
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at 4°C prior to restoration
- For extended storage aliquot contents and freeze at -20°C or below
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Deoxyribonuclease I is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified Deoxyribonuclease I [Bovine Pancreas]
- Cross reactivity against Deoxyribonuclease I from other tissues and species may occur but have not been specifically determined
- Internucleosomal DNA fragmentation following the activation of endonucleases is the common end point of apoptosis
- DNase I, a Ca2+/Mg2+-dependent endonuclease ubiquitously expressed in mammalian tissues, has been implicated to mediate internucleosomal DNA degradation in human cells undergoing apoptosis
- DNase I is highly polymorphic, and at least six alleles of DNase I are known
- DNase II, the ubiquitously expressed acidic deoxyribonuclease, acts downstream of caspase activation and may also induce DNA digestion during apoptosis
- DNase I cleaves DNA to 5'-phosphodinucleotide and 5'-phospho- oligonucleotide end-products, whereas DNase II cleaves DNA to 3'-phosphomononucleotide and 3'-phosphooligonucleotide end-products
- The mechanism by which DNase II cuts DNA is similar to DNase I, which produces nicks rather than double-strand cuts
- DNase II is usually present in cytoplasm of epithelial cells, but it appears concentrated in the nuclei of lens fibers
- In contrast, DNase I is always concentrated in nuclei of epithelial and fiber cells.
Compare Similar Items
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Antigen: Deoxyribonuclease I
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Rabbit
Target Species: Bovine
Gene Accession No.: P00639
Gene ID (Entrez): 282217
Immunogen: Deoxyribonuclease I [Bovine Pancreas]
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: DNASE1
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I
Gene Symbols: DNASE1
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Deoxyribonuclease I
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Bovine
Gene Accession No.:
P00639
Gene ID (Entrez):
282217
Immunogen:
Deoxyribonuclease I [Bovine Pancreas]
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
DNASE1
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I
Gene Symbols:
DNASE1
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: IFN Induced GTPase-like Protein
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: __
Gene ID (Entrez): 225594
Immunogen: IFN Induced GTPase Like Protein was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal region of mouse IFN Induced GTPase Like Protein.
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Gm4841
Concentration: 86.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.5M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: Gm4841
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
IFN Induced GTPase-like Protein
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
__
Gene ID (Entrez):
225594
Immunogen:
IFN Induced GTPase Like Protein was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal region of mouse IFN Induced GTPase Like Protein.
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Gm4841
Concentration:
86.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.5M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
Gm4841
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: DbpB
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-B protein.
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
DbpB
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-B protein.
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: alpha-1-Anti-Trypsin
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Goat
Target Species: Human
Gene Accession No.: P01009
Gene ID (Entrez): 5265
Immunogen: Anti-alpha 1 Anti-Trypsin Antibody was produced by repeated immunizations with native alpha1-Anti-Trypsin protein from human plasma.
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: SERPINA1
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha-1 antitrypsin; Alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; Alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); Alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; Alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; Serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; Serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1
Gene Symbols: SERPINA1
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
alpha-1-Anti-Trypsin
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P01009
Gene ID (Entrez):
5265
Immunogen:
Anti-alpha 1 Anti-Trypsin Antibody was produced by repeated immunizations with native alpha1-Anti-Trypsin protein from human plasma.
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
SERPINA1
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha-1 antitrypsin; Alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; Alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); Alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; Alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; Serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; Serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1
Gene Symbols:
SERPINA1
Primary or Secondary:
Primary
Product Type:
Antibody