7190781

MEK1 C-Term Monoclonal Antibody (13B6.G12), Biotin, Rockland™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

MEK1 C-Term

Concentration

1 mg/mL

Classification

Monoclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias

CFC3; dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; MAP2K1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Gene Symbols

Map2k1

Isotype

IgG1 κ

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene

Map2k1

Clone

13B6.G12

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Mouse

Target Species

Human, Mouse, Rat

Gene Accession No.

P31938, Q01986, Q02750

Gene ID (Entrez)

170851, 26395, 5604

Immunogen

Anti-MEK1 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the C-terminus conjugated to KLH.

Primary or Secondary

Primary

Product Type

Antibody

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Description

  • Store vial at 4°C prior to restoration
  • For extended storage aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Reacts specifically with human MEK1
  • Anti-MEK1 is purified from tissue culture supernatant by protein A purification
  • Cross reactivity is expected to occur with human, mouse, and rat based on sequence identity of the peptide immunogen
  • This antibody does not react with the MEK2 isoform
  • MEK1/mitogen activated protein kinase/ERK kinase 1/microtubule-associated protein 2 kinase is a dual specificity kinase and catalyzes both a threonine and a tyrosine residue on MAP kinases ERK1 and ERK2
  • Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1
  • It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines
  • Mutations in the gene can lead to cardiofaciocutaneous syndrome.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7190781

Mouse Monoclonal Antibody...


Antigen:
MEK1 C-Term

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; MAP2K1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Gene Symbols:
Map2k1

Isotype:
IgG1 κ

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
Map2k1

Clone:
13B6.G12

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Mouse

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P31938, Q01986, Q02750

Gene ID (Entrez):
170851, 26395, 5604

Immunogen:
Anti-MEK1 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the C-terminus conjugated to KLH.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190783

Rabbit Polyclonal Antibody...


Antigen:
IL-1 Receptor Antagonist

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Anakinra; CD121A; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; IL1 receptor antagonist; IL1F3; IL1R; IL1RA; Il-1ra; IL1-RA; IL-1ra3; IL-1R-alpha; Il1rn; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist

Gene Symbols:
IL1RN

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
IL1RN

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P18510

Gene ID (Entrez):
3557

Immunogen:
The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human sIL-1Ra produced in E.coli.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190783

Rabbit Polyclonal Antibody...


Antigen:
IL-1 Receptor Antagonist

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Anakinra; CD121A; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; IL1 receptor antagonist; IL1F3; IL1R; IL1RA; Il-1ra; IL1-RA; IL-1ra3; IL-1R-alpha; Il1rn; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist

Gene Symbols:
IL1RN

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
IL1RN

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P18510

Gene ID (Entrez):
3557

Immunogen:
The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human sIL-1Ra produced in E.coli.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190786

Rabbit Polyclonal Antibody...


Antigen:
NAG-1

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
GDF15; GDF-15; growth differentiation factor 15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; Sbf

Gene Symbols:
Gdf15

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Gdf15

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q99988

Gene ID (Entrez):
9518

Immunogen:
__

Primary or Secondary:
Primary

Product Type:
Antibody