7191184
IL-27/p28 Monoclonal Antibody (3H12.F10), Rockland™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Mouse IL-27/p28
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420
Gene Symbols
Ebi3, IL27
Isotype
IgG2a κ
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
IL27
Clone
3H12.F10
Applications
ELISA, Flow Cytometry, Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Mouse
Gene Accession No.
O35228, Q8K3I6
Gene ID (Entrez)
246779, 50498
Immunogen
Anti-IL-27/p28 monoclonal antibody was produced in rats by repeated immunizations with mature length recombinant mouse p28 protein (produced in E.coli) followed by hybridoma development.
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- IL-27 / p28 antibody is purified by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
- This antibody is specific for mouse and rat p28 protein
- Cross-reactivity with IL-27 from other sources has not been determined
- IL-27 (Interleukin 27) is a cytokine belonging to the IL-12 family, and is a heterodimeric cytokine composed of EBI3 and p28 subunits
- IL-27 is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines
- IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing expression of the transcription factor T-bet and up regulating IL-12R beta2, which in turn suppresses Th2 and Th17 differentiation and proliferation
- IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines
- IL-27 acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting IL-27 involvement in the regulation of immune processes
- It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet
- In humans, the gene is located on the p arm of chromosome 16.
Compare Similar Items
Show Difference
Antigen: Mouse IL-27/p28
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420
Gene Symbols: Ebi3, IL27
Isotype: IgG2a κ
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: IL27
Clone: 3H12.F10
Applications: ELISA, Flow Cytometry, Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Mouse
Gene Accession No.: O35228, Q8K3I6
Gene ID (Entrez): 246779, 50498
Immunogen: Anti-IL-27/p28 monoclonal antibody was produced in rats by repeated immunizations with mature length recombinant mouse p28 protein (produced in E.coli) followed by hybridoma development.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Mouse IL-27/p28
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420
Gene Symbols:
Ebi3, IL27
Isotype:
IgG2a κ
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
IL27
Clone:
3H12.F10
Applications:
ELISA, Flow Cytometry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
O35228, Q8K3I6
Gene ID (Entrez):
246779, 50498
Immunogen:
Anti-IL-27/p28 monoclonal antibody was produced in rats by repeated immunizations with mature length recombinant mouse p28 protein (produced in E.coli) followed by hybridoma development.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: ATDC Ac-K116
Concentration: 0.67 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 1110047J21Rik; 2810431N19Rik; 4732461M22Rik; AI119726; Ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein; ATDC; FLJ36085; TRIM29; tripartite motif containing 29; tripartite motif protein 29; tripartite motif protein TRIM29; tripartite motif-containing 29; Tripartite motif-containing protein 29
Gene Symbols: Trim29
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Trim29
Clone: __
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Chimpanzee, Equine, Human, Rhesus Monkey
Gene Accession No.: Q14134
Gene ID (Entrez): 100071461, 23650, 451615, 525062, 705796
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
ATDC Ac-K116
Concentration:
0.67 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
1110047J21Rik; 2810431N19Rik; 4732461M22Rik; AI119726; Ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein; ATDC; FLJ36085; TRIM29; tripartite motif containing 29; tripartite motif protein 29; tripartite motif protein TRIM29; tripartite motif-containing 29; Tripartite motif-containing protein 29
Gene Symbols:
Trim29
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Trim29
Clone:
__
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Chimpanzee, Equine, Human, Rhesus Monkey
Gene Accession No.:
Q14134
Gene ID (Entrez):
100071461, 23650, 451615, 525062, 705796
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: L-Asparaginase
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: __
Gene Symbols: __
Isotype: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Clone: __
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Rabbit
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Anti-Asparaginase Antibody was produced by repeated immunizations with E. coli Asparaginase protein.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
L-Asparaginase
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Isotype:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Clone:
__
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Anti-Asparaginase Antibody was produced by repeated immunizations with E. coli Asparaginase protein.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Cas 9
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Gene Symbols: __
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: __
Clone: __
Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Cas 9
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Gene Symbols:
__
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
__
Clone:
__
Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody