7192893

CD49b (Integrin alpha 2) Monoclonal Antibody (DX5), PE-Cyanine5.5, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD49b (Integrin alpha 2)

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2

Gene Symbols

Itga2

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Itga2

Clone

DX5

Applications

Flow Cytometry

Conjugate

PE-Cyanine5.5

Host Species

Rat

Target Species

Mouse

Gene Accession No.

Q62469

Gene ID (Entrez)

16398

Isotype

IgM κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family
  • It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex
  • VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways
  • It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation
  • CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells
  • It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.

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7192893

Rat Monoclonal Antibody...


Antigen:
CD49b (Integrin alpha 2)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2

Gene Symbols:
Itga2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Itga2

Clone:
DX5

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine5.5

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q62469

Gene ID (Entrez):
16398

Isotype:
IgM κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
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Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415

Gene Symbols:
TMEM119

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
TMEM119

Clone:
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Applications:
Flow Cytometry

Conjugate:
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Host Species:
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Target Species:
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Gene Alias:
CD162; CLA; Cutaneous lymphocyte associated antigen; cutaneous lymphocyte-associated associated antigen; leukocyte cell surface adhesion molecule; P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1 propeptide; P-selectin glycoprotein ligand-1; Psgl1; Psgl-1; Selectin P ligand; selectin, platelet (p-selectin) ligand; Selp1; SELPG; Selpl; SELPLG

Gene Symbols:
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Primary or Secondary:
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Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
SELPLG

Clone:
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Applications:
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Conjugate:
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Host Species:
Rat

Target Species:
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20345

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