Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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KIR2DL3/CD158b2
1 mg/mL
Flow Cytometry, Immunoprecipitation
Unconjugated
Mouse
Apoptosis
PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide
CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor
KIR2DL3
IgG1
Protein A or G purified
NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.
GL183
Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500
Monoclonal
Purified
RUO
Human
P43628
3804
NK cell clone E57
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.