7199778

KIR2DL3/CD158b2 Antibody (GL183), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

KIR2DL3/CD158b2

Concentration

1 mg/mL

Applications

Flow Cytometry, Immunoprecipitation

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Apoptosis

Formulation

PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide

Gene Alias

CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor

Gene Symbols

KIR2DL3

Isotype

IgG1

Purification Method

Protein A or G purified

Test Specificity

NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Clone

GL183

Dilution

Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Accession No.

P43628

Gene ID (Entrez)

3804

Immunogen

NK cell clone E57

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Description

  • KIR2DL3/CD158b2 Monoclonal specifically detects KIR2DL3/CD158b2 in Human samples
  • It is validated for Flow Cytometry, Immunoprecipitation.

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Fischer Scientific

7199778

Mouse Monoclonal Antibody...


Antigen:
KIR2DL3/CD158b2

Concentration:
1 mg/mL

Applications:
Flow Cytometry, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis

Formulation:
PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide

Gene Alias:
CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor

Gene Symbols:
KIR2DL3

Isotype:
IgG1

Purification Method:
Protein A or G purified

Test Specificity:
NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Clone:
GL183

Dilution:
Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P43628

Gene ID (Entrez):
3804

Immunogen:
NK cell clone E57

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Sigma Aldrich

719978

acid terminated, Mw 10,000-18,000...


Antigen:
__

Concentration:
__

Applications:
__

Conjugate:
__

Host Species:
__

Research Discipline:
__

Formulation:
__

Gene Alias:
__

Gene Symbols:
__

Isotype:
__

Purification Method:
__

Test Specificity:
__

Clone:
__

Dilution:
__

Classification:
__

Form:
__

Regulatory Status:
__

Target Species:
__

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
__

Primary or Secondary:
__

Content And Storage:
__

Img

Fischer Scientific

7199780

Rat Monoclonal Antibody...


Antigen:
Epstein Barr Virus

Concentration:
1.0 mg/mL

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Rat

Research Discipline:
__

Formulation:
__

Gene Alias:
Epstein Barr Virus, Human herpesvirus type 4, Hypothetical protein BALF1

Gene Symbols:
__

Isotype:
IgG1

Purification Method:
Protein G purified

Test Specificity:
Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin

Clone:
15F9

Dilution:
Western Blot 1:100-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Virus

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Bacterial TrpE-LMP2A fusion protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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7199782

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Antigen:
Cytokeratin 8

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Frozen), Flow Cytometry, Immunohistochemistry, Western Blot, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
__

Formulation:
__

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Gene Symbols:
KRT8

Isotype:
IgG1

Purification Method:
Affinity Purified

Test Specificity:
Recognizes most of the basic (Type II) keratins, HMW cytokeratins. It is broadly reactive and stains positively almost all epithelia and their neoplasms. AE3 reacts with all layers of epidermis (basal layer and above). The antibody is an excellent marker for distinguishing carcinomas from non-epithelial tumours. It has been used for studying the immunolocalisation of epidermal keratins, tissue distribution of keratins, various diseases of epidermis, oral mucosa and other epithelia and other epithelia development.

Clone:
AE3

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen

Classification:
Monoclonal

Form:
__

Regulatory Status:
RUO

Target Species:
Mouse, Primate, Rabbit, Chicken, Bovine, Rat, Human

Gene Accession No.:
__

Gene ID (Entrez):
3856

Immunogen:
Human epidermal cells

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.