7200912
LAG-3 Antibody (C9B7W) - BSA Free, Novus Biologicals™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
LAG-3
Concentration
1.0 mg/mL
Applications
Flow Cytometry
Conjugate
Unconjugated
Host Species
Rat
Research Discipline
Adaptive Immunity, Immunology, Innate Immunity
Gene Accession No.
Q61790
Gene ID (Entrez)
3902
Immunogen
Murine CD223 Ig fusion protein
Primary or Secondary
Primary
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen
57 kDa
Clone
C9B7W
Dilution
Flow Cytometry 1:50 - 1:200
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Mouse
Gene Alias
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Gene Symbols
LAG3
Isotype
IgG1
Purification Method
Protein G purified
Test Specificity
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Related Products
Description
- Description LAG-3 Monoclonal specifically detects LAG-3 in Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
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Antigen: LAG-3
Concentration: 1.0 mg/mL
Applications: Flow Cytometry
Conjugate: Unconjugated
Host Species: Rat
Research Discipline: Adaptive Immunity, Immunology, Innate Immunity
Gene Accession No.: Q61790
Gene ID (Entrez): 3902
Immunogen: Murine CD223 Ig fusion protein
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 57 kDa
Clone: C9B7W
Dilution: Flow Cytometry 1:50 - 1:200
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Gene Symbols: LAG3
Isotype: IgG1
Purification Method: Protein G purified
Test Specificity: NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Antigen:
LAG-3
Concentration:
1.0 mg/mL
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Host Species:
Rat
Research Discipline:
Adaptive Immunity, Immunology, Innate Immunity
Gene Accession No.:
Q61790
Gene ID (Entrez):
3902
Immunogen:
Murine CD223 Ig fusion protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
57 kDa
Clone:
C9B7W
Dilution:
Flow Cytometry 1:50 - 1:200
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Gene Symbols:
LAG3
Isotype:
IgG1
Purification Method:
Protein G purified
Test Specificity:
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Antigen: CD98
Concentration: 1.0 mg/mL
Applications: Immunohistochemistry, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cell Biology, Cellular Markers, Immunology, Lipid and Metabolism, Plasma Membrane Markers, Signal Transduction
Gene Accession No.: P08195
Gene ID (Entrez): 6520
Immunogen: HOON pre-B leukaemia cell line.
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: __
Clone: 44D7
Dilution: Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: 4F2, 4F2hc, 4T2HC, antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC, CD98, CD98 antigen, CD98 heavy chain, CD98HC, heavy chain, Lymphocyte activation antigen 4F2 large subunit, MDU1antigen defined by monoclonal 4F2, heavy chain, monoclonal 44D7, NACAE4F2 cell-surface antigen heavy chain, solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen
Gene Symbols: SLC3A2
Isotype: IgG1
Purification Method: Protein G purified
Test Specificity: The reacts with the heavy chain of the CD98 molecule. It binds to all cell lines in culture and to activated T cells.
Antigen:
CD98
Concentration:
1.0 mg/mL
Applications:
Immunohistochemistry, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cell Biology, Cellular Markers, Immunology, Lipid and Metabolism, Plasma Membrane Markers, Signal Transduction
Gene Accession No.:
P08195
Gene ID (Entrez):
6520
Immunogen:
HOON pre-B leukaemia cell line.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
__
Clone:
44D7
Dilution:
Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
4F2, 4F2hc, 4T2HC, antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC, CD98, CD98 antigen, CD98 heavy chain, CD98HC, heavy chain, Lymphocyte activation antigen 4F2 large subunit, MDU1antigen defined by monoclonal 4F2, heavy chain, monoclonal 44D7, NACAE4F2 cell-surface antigen heavy chain, solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen
Gene Symbols:
SLC3A2
Isotype:
IgG1
Purification Method:
Protein G purified
Test Specificity:
The reacts with the heavy chain of the CD98 molecule. It binds to all cell lines in culture and to activated T cells.
Antigen: LIM Kinase 1 (p Thr508)
Concentration: 1.0 mg/mL
Applications: Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Breast Cancer, Cancer, Phospho Specific, Protein Kinase
Gene Accession No.: P53667
Gene ID (Entrez): 3984
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 72 kDa
Clone: __
Dilution: Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100
Classification: Polyclonal
Form: __
Regulatory Status: RUO
Target Species: Mouse, Rat, Human
Gene Alias: EC 2.7.11.1, LIM domain kinase 1, LIM motif-containing protein kinase, LIMKLIMK-1
Gene Symbols: LIMK1
Isotype: IgG
Purification Method: Affinity Purified
Test Specificity: __
Antigen:
LIM Kinase 1 (p Thr508)
Concentration:
1.0 mg/mL
Applications:
Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Breast Cancer, Cancer, Phospho Specific, Protein Kinase
Gene Accession No.:
P53667
Gene ID (Entrez):
3984
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
72 kDa
Clone:
__
Dilution:
Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100
Classification:
Polyclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Mouse, Rat, Human
Gene Alias:
EC 2.7.11.1, LIM domain kinase 1, LIM motif-containing protein kinase, LIMKLIMK-1
Gene Symbols:
LIMK1
Isotype:
IgG
Purification Method:
Affinity Purified
Test Specificity:
__
Antigen: LIM Kinase 1 (p Thr508)
Concentration: 1.0 mg/mL
Applications: Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Breast Cancer, Cancer, Phospho Specific, Protein Kinase
Gene Accession No.: P53667
Gene ID (Entrez): 3984
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 72 kDa
Clone: __
Dilution: Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100
Classification: Polyclonal
Form: __
Regulatory Status: RUO
Target Species: Mouse, Rat, Human
Gene Alias: EC 2.7.11.1, LIM domain kinase 1, LIM motif-containing protein kinase, LIMKLIMK-1
Gene Symbols: LIMK1
Isotype: IgG
Purification Method: Affinity Purified
Test Specificity: __
Antigen:
LIM Kinase 1 (p Thr508)
Concentration:
1.0 mg/mL
Applications:
Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Breast Cancer, Cancer, Phospho Specific, Protein Kinase
Gene Accession No.:
P53667
Gene ID (Entrez):
3984
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
72 kDa
Clone:
__
Dilution:
Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100
Classification:
Polyclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Mouse, Rat, Human
Gene Alias:
EC 2.7.11.1, LIM domain kinase 1, LIM motif-containing protein kinase, LIMKLIMK-1
Gene Symbols:
LIMK1
Isotype:
IgG
Purification Method:
Affinity Purified
Test Specificity:
__