7244894
TRAIL-R2 (DR5) (soluble) Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TRAIL-R2 (DR5) (soluble)
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O14763
Gene ID (Entrez)
8795
Immunogen
E.coli-derived Recombinant Human sTRAIL Receptor-2
Purification Method
Antigen affinity chromatography
Gene
TNFRSF10B
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Gene Symbols
TNFRSF10B
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MESALITQQD LAPQQRVAPQ QKRSSPSEGL CPPGHHISED GRDCISCKYG QDYSTHWNDL LFCLRCTRCD SGEVELSPCT TTRNTVCQCE EGTFREEDSP EMCRKCRTGC PRGMVKVGDC TPWSDIECVH KES
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human sTRAIL Receptor-2
- Anti-Human sTRAIL Receptor-2-specific antibody was purified by affinity chromatography employing an immobilized Human sTRAIL Receptor-2 matrix
- Sandwich ELISA: To detect Human sTRAIL Receptor-2 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human sTRAIL Receptor-2 (500-P299Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sTRAIL Receptor-2
- Western Blot: To detect hsTRAIL Receptor-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hsTRAIL Receptor-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis
- DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain
- DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal
- Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5
- Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found
- Overexpression of DR5 induces apoptosis and activates NF-kappa-B
- DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen
- Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.
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Antigen: TRAIL-R2 (DR5) (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O14763
Gene ID (Entrez): 8795
Immunogen: E.coli-derived Recombinant Human sTRAIL Receptor-2
Purification Method: Antigen affinity chromatography
Gene: TNFRSF10B
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Gene Symbols: TNFRSF10B
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
TRAIL-R2 (DR5) (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O14763
Gene ID (Entrez):
8795
Immunogen:
E.coli-derived Recombinant Human sTRAIL Receptor-2
Purification Method:
Antigen affinity chromatography
Gene:
TNFRSF10B
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Gene Symbols:
TNFRSF10B
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CXCL12 alpha (SDF-1 alpha)
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Mouse
Gene Accession No.: P40224
Gene ID (Entrez): 20315
Immunogen: E.coli-derived, 7.9 kDa Recombinant Murine SDF-1alpha (CXCL12)
Purification Method: Antigen affinity chromatography
Gene: CXCL12
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1a; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1a; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
Gene Symbols: CXCL12
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CXCL12 alpha (SDF-1 alpha)
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Mouse
Gene Accession No.:
P40224
Gene ID (Entrez):
20315
Immunogen:
E.coli-derived, 7.9 kDa Recombinant Murine SDF-1alpha (CXCL12)
Purification Method:
Antigen affinity chromatography
Gene:
CXCL12
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1a; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1a; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
Gene Symbols:
CXCL12
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: TWEAK
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Human
Gene Accession No.: O43508
Gene ID (Entrez): 8742
Immunogen: E.coli-derived, 17.0 kDa Recombinant Human TWEAK
Purification Method: Antigen affinity chromatography
Gene: Tnfsf12
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Gene Symbols: Tnfsf12
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
TWEAK
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
O43508
Gene ID (Entrez):
8742
Immunogen:
E.coli-derived, 17.0 kDa Recombinant Human TWEAK
Purification Method:
Antigen affinity chromatography
Gene:
Tnfsf12
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Gene Symbols:
Tnfsf12
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IL-11
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P20809
Gene ID (Entrez): 3589
Immunogen: E.coli-derived Recombinant Human IL-11
Purification Method: Antigen affinity chromatography
Gene: IL11
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: adipogenesis inhibitory factor; AGIF; il 11; IL10RA; Il11; IL-11; IL11 inhibitor; IL-11ra; ILN; Interleukin; interleukin 11; Interleukin11; interleukin-11; MGC2146; Oprelvekin
Gene Symbols: IL11
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-11
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P20809
Gene ID (Entrez):
3589
Immunogen:
E.coli-derived Recombinant Human IL-11
Purification Method:
Antigen affinity chromatography
Gene:
IL11
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
adipogenesis inhibitory factor; AGIF; il 11; IL10RA; Il11; IL-11; IL11 inhibitor; IL-11ra; ILN; Interleukin; interleukin 11; Interleukin11; interleukin-11; MGC2146; Oprelvekin
Gene Symbols:
IL11
Primary or Secondary:
Primary
Content And Storage:
-20°C