7244925
TNF alpha Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
TNF alpha
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Rat
Gene Accession No.
P16599
Gene ID (Entrez)
24835
Immunogen
E.coli-derived, 17.3 kDa Recombinant Rat TNF-alpha
Purification Method
Antigen affinity chromatography
Gene
Tnf
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols
Tnf
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MLRSSSQNSS DKPVAHVVAN HQAEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLIY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VSLLSAIKSP CPKDTPEGAE LKPWYEPMYL GGVFQLEKGD LLSAEVNLPK YLDITESGQV YFGVIAL
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Rat TNF-alpha
- Anti-Rat TNF-alpha-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Rat TNF-alpha by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Rat TNF-alpha (500-P72) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat TNF-alpha
- Western Blot: To detect Rat TNF-alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Rat TNF-alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P72BT-1MG will be provided as 2 x 500 μg TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
- This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
- TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
- TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
- Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
- Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
- TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
- This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Compare Similar Items
Show Difference
Antigen: TNF alpha
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P16599
Gene ID (Entrez): 24835
Immunogen: E.coli-derived, 17.3 kDa Recombinant Rat TNF-alpha
Purification Method: Antigen affinity chromatography
Gene: Tnf
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols: Tnf
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
TNF alpha
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P16599
Gene ID (Entrez):
24835
Immunogen:
E.coli-derived, 17.3 kDa Recombinant Rat TNF-alpha
Purification Method:
Antigen affinity chromatography
Gene:
Tnf
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols:
Tnf
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: SCF
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P21583
Gene ID (Entrez): 4254
Immunogen: E.coli-derived, 18.4 kDa Recombinant Human SCF
Purification Method: Antigen affinity chromatography
Gene: KITLG
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols: KITLG
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
SCF
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P21583
Gene ID (Entrez):
4254
Immunogen:
E.coli-derived, 18.4 kDa Recombinant Human SCF
Purification Method:
Antigen affinity chromatography
Gene:
KITLG
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols:
KITLG
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: WISP2
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O76076
Gene ID (Entrez): 8839
Immunogen: E.coli-derived Recombinant Human CTGFL/WISP-2
Purification Method: Antigen affinity chromatography
Gene: CCN5
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CCN family member 5; CCN family protein COP-1; Ccn5; connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; Cop1; Crgr4; CT58; CTGFL; CTGF-L; Rcop1; UNQ228/PRO261; WISP2; WISP-2; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2
Gene Symbols: CCN5
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
WISP2
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O76076
Gene ID (Entrez):
8839
Immunogen:
E.coli-derived Recombinant Human CTGFL/WISP-2
Purification Method:
Antigen affinity chromatography
Gene:
CCN5
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CCN family member 5; CCN family protein COP-1; Ccn5; connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; Cop1; Crgr4; CT58; CTGFL; CTGF-L; Rcop1; UNQ228/PRO261; WISP2; WISP-2; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2
Gene Symbols:
CCN5
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IL-1 beta
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: Q63264
Gene ID (Entrez): 24494
Immunogen: E.coli-derived Recombinant Rat IL-1beta
Purification Method: Antigen affinity chromatography
Gene: IL1B
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: __
Gene Symbols: IL1B
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-1 beta
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
Q63264
Gene ID (Entrez):
24494
Immunogen:
E.coli-derived Recombinant Rat IL-1beta
Purification Method:
Antigen affinity chromatography
Gene:
IL1B
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
__
Gene Symbols:
IL1B
Primary or Secondary:
Primary
Content And Storage:
-20°C