7244922
RANKL (soluble) Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
RANKL (soluble)
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Mouse
Gene Accession No.
O35235
Gene ID (Entrez)
21943
Immunogen
E.coli-derived Recombinant Murine sRANK Ligand
Purification Method
Antigen affinity chromatography
Gene
TNFSF11
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Gene Symbols
TNFSF11
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: PAMMEGSWLD VAQRGKPEAQ PFAHLTINAA SIPSGSHKVT LSSWYHDRGW AKISNMTLSN GKLRVNQDGF YYLYANICFR HHETSGSVPT DYLQLMVYVV KTSIKIPSSH NLMKGGSTKN WSGNSEFHFY SINVGGFFKL RAGEEISIQV SNPSLLDPDQ DATYFGAFKV QDID
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine sRANK Ligand
- Anti-Murine sRANK Ligand-specific antibody was purified by affinity chromatography employing an immobilized Murine sRANK Ligand matrix
- Sandwich ELISA: To detect Murine sRANK Ligand by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine sRANKL (500-P63Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine sRANK Ligand
- Western Blot: To detect Murine sRANK Ligand by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine sRANK Ligand is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
- This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
- T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
- This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
- Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
- The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
- Two alternatively spliced transcript variants have been found.
Compare Similar Items
Show Difference
Antigen: RANKL (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: O35235
Gene ID (Entrez): 21943
Immunogen: E.coli-derived Recombinant Murine sRANK Ligand
Purification Method: Antigen affinity chromatography
Gene: TNFSF11
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Gene Symbols: TNFSF11
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
RANKL (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
O35235
Gene ID (Entrez):
21943
Immunogen:
E.coli-derived Recombinant Murine sRANK Ligand
Purification Method:
Antigen affinity chromatography
Gene:
TNFSF11
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Gene Symbols:
TNFSF11
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: VEGFB
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P49765
Gene ID (Entrez): 7423
Immunogen: E.coli-derived Recombinant Human VEGF-B
Purification Method: Antigen affinity chromatography
Gene: VEGFB
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: flt-1/VEGFR1 ligand; vascular endothelial growth factor B; vascular endothelial growth factor B167 precursor; vascular endothelial growth factor B186 precursor; vascular endothelial growth factor-B; Vegfb; VEGF-B; VEGFL; VEGF-related factor; Vrf
Gene Symbols: VEGFB
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
VEGFB
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P49765
Gene ID (Entrez):
7423
Immunogen:
E.coli-derived Recombinant Human VEGF-B
Purification Method:
Antigen affinity chromatography
Gene:
VEGFB
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
flt-1/VEGFR1 ligand; vascular endothelial growth factor B; vascular endothelial growth factor B167 precursor; vascular endothelial growth factor B186 precursor; vascular endothelial growth factor-B; Vegfb; VEGF-B; VEGFL; VEGF-related factor; Vrf
Gene Symbols:
VEGFB
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Chymotrypsin
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q99895
Gene ID (Entrez): 11330
Immunogen: Purified human pancreatic Chymotrypsin.
Purification Method: Protein A
Gene: CTRC
Concentration: 2.0 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: 1810044E12Rik; caldecrin; chymotrypsin C; chymotrypsin C (caldecrin); chymotrypsin-C; CLCR; Ctrc; ELA4; elastase 4; elastase IV; preprocaldecrin; serum calcium decreasing factor; serum calcium-decreasing factor
Gene Symbols: CTRC
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Chymotrypsin
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q99895
Gene ID (Entrez):
11330
Immunogen:
Purified human pancreatic Chymotrypsin.
Purification Method:
Protein A
Gene:
CTRC
Concentration:
2.0 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
1810044E12Rik; caldecrin; chymotrypsin C; chymotrypsin C (caldecrin); chymotrypsin-C; CLCR; Ctrc; ELA4; elastase 4; elastase IV; preprocaldecrin; serum calcium decreasing factor; serum calcium-decreasing factor
Gene Symbols:
CTRC
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Antigen: Chymotrypsin
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q99895
Gene ID (Entrez): 11330
Immunogen: Purified human pancreatic Chymotrypsin.
Purification Method: Protein A
Gene: CTRC
Concentration: 2.0 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: 1810044E12Rik; caldecrin; chymotrypsin C; chymotrypsin C (caldecrin); chymotrypsin-C; CLCR; Ctrc; ELA4; elastase 4; elastase IV; preprocaldecrin; serum calcium decreasing factor; serum calcium-decreasing factor
Gene Symbols: CTRC
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Chymotrypsin
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q99895
Gene ID (Entrez):
11330
Immunogen:
Purified human pancreatic Chymotrypsin.
Purification Method:
Protein A
Gene:
CTRC
Concentration:
2.0 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
1810044E12Rik; caldecrin; chymotrypsin C; chymotrypsin C (caldecrin); chymotrypsin-C; CLCR; Ctrc; ELA4; elastase 4; elastase IV; preprocaldecrin; serum calcium decreasing factor; serum calcium-decreasing factor
Gene Symbols:
CTRC
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles