7245036
IGF1 Polyclonal Antibody, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IGF1
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Goat
Target Species
Mouse
Gene Accession No.
P05017
Gene ID (Entrez)
16000
Immunogen
E.coli-derived Recombinant Murine IGF-I
Purification Method
Antigen affinity chromatography
Gene
IGF1
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Gene Symbols
IGF1
Primary or Secondary
Primary
Content And Storage
-20°C
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Description
- AA Sequence of recombinant protein: GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine IGF-I
- Anti-Murine IGF-I-specific antibody was purified by affinity chromatography employing an immobilized Murine IGF-I matrix
- Sandwich ELISA: To detect Murine IGF-I by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine IGF-I (500-P157GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IGF-I
- Western Blot: To detect Murine IGF-I by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine IGF-I is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
- A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
- Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
- IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
- In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
- IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
- Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
- Low levels of IGF1 have been linked to Alzheimer's disease
- IGF1 is processed from a precursor, bound by a specific receptor, and secreted
- Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.
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Antigen: IGF1
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Mouse
Gene Accession No.: P05017
Gene ID (Entrez): 16000
Immunogen: E.coli-derived Recombinant Murine IGF-I
Purification Method: Antigen affinity chromatography
Gene: IGF1
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Gene Symbols: IGF1
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IGF1
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Mouse
Gene Accession No.:
P05017
Gene ID (Entrez):
16000
Immunogen:
E.coli-derived Recombinant Murine IGF-I
Purification Method:
Antigen affinity chromatography
Gene:
IGF1
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Gene Symbols:
IGF1
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: VEGF-165
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Human
Gene Accession No.: P15692
Gene ID (Entrez): 7422
Immunogen: E.coli-derived, 38.2 kDa Recombinant Human VEGF 165
Purification Method: Antigen affinity chromatography
Gene: Vegfa
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: H-VEGF-165, MVCD1, M-VEGF-165, vascular endothelial growth factor 165b, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor, VEGF, VEGF164, VEGF165, Vegfa, VEGF-A, VPF
Gene Symbols: Vegfa
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
VEGF-165
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P15692
Gene ID (Entrez):
7422
Immunogen:
E.coli-derived, 38.2 kDa Recombinant Human VEGF 165
Purification Method:
Antigen affinity chromatography
Gene:
Vegfa
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
H-VEGF-165, MVCD1, M-VEGF-165, vascular endothelial growth factor 165b, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor, VEGF, VEGF164, VEGF165, Vegfa, VEGF-A, VPF
Gene Symbols:
Vegfa
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: VEGF-165
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Human
Gene Accession No.: P15692
Gene ID (Entrez): 7422
Immunogen: E.coli-derived, 38.2 kDa Recombinant Human VEGF 165
Purification Method: Antigen affinity chromatography
Gene: Vegfa
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: H-VEGF-165, MVCD1, M-VEGF-165, vascular endothelial growth factor 165b, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor, VEGF, VEGF164, VEGF165, Vegfa, VEGF-A, VPF
Gene Symbols: Vegfa
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
VEGF-165
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P15692
Gene ID (Entrez):
7422
Immunogen:
E.coli-derived, 38.2 kDa Recombinant Human VEGF 165
Purification Method:
Antigen affinity chromatography
Gene:
Vegfa
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
H-VEGF-165, MVCD1, M-VEGF-165, vascular endothelial growth factor 165b, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor, VEGF, VEGF164, VEGF165, Vegfa, VEGF-A, VPF
Gene Symbols:
Vegfa
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: HBEGF
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q99075
Gene ID (Entrez): 1839
Immunogen: E.coli-derived, 9.7 kDa Recombinant Human HB-EGF
Purification Method: Antigen affinity chromatography
Gene: HBEGF
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: AW047313; Diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); DTR; DT-R; DTS; DTSF; GFHB; hb egf; HBEGF; Hb-egf; Hegfl; heparin binding EGF like growth factor; heparin binding epidermal growth factor-like growth factor; heparin-binding EGF-like growth factor; heparin-binding epidermal -growth - like growth factor; heparin-binding epidermal growth factor; heparin-binding epidermal -growth factor; proheparin-binding EGF-like growth factor
Gene Symbols: HBEGF
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
HBEGF
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q99075
Gene ID (Entrez):
1839
Immunogen:
E.coli-derived, 9.7 kDa Recombinant Human HB-EGF
Purification Method:
Antigen affinity chromatography
Gene:
HBEGF
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
AW047313; Diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); DTR; DT-R; DTS; DTSF; GFHB; hb egf; HBEGF; Hb-egf; Hegfl; heparin binding EGF like growth factor; heparin binding epidermal growth factor-like growth factor; heparin-binding EGF-like growth factor; heparin-binding epidermal -growth - like growth factor; heparin-binding epidermal growth factor; heparin-binding epidermal -growth factor; proheparin-binding EGF-like growth factor
Gene Symbols:
HBEGF
Primary or Secondary:
Primary
Content And Storage:
-20°C