7245496
IGF1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IGF1
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P05019
Gene ID (Entrez)
3479
Immunogen
E.coli-derived Recombinant Human IGF-I
Purification Method
Antigen affinity chromatography
Gene
IGF1
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Gene Symbols
IGF1
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-I
- Anti-Human IGF-I-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human IGF-I by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IGF-I (500-P11) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IGF-I
- Western Blot: To detect hIGF-I by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIGF-I is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P11BT-1MG will be provided as 2 x 500 μg IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
- A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
- Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
- IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
- In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
- IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
- Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
- Low levels of IGF1 have been linked to Alzheimer's disease
- IGF1 is processed from a precursor, bound by a specific receptor, and secreted
- Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.
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Antigen: IGF1
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P05019
Gene ID (Entrez): 3479
Immunogen: E.coli-derived Recombinant Human IGF-I
Purification Method: Antigen affinity chromatography
Gene: IGF1
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Gene Symbols: IGF1
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IGF1
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P05019
Gene ID (Entrez):
3479
Immunogen:
E.coli-derived Recombinant Human IGF-I
Purification Method:
Antigen affinity chromatography
Gene:
IGF1
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Gene Symbols:
IGF1
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Resistin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Human
Gene Accession No.: Q9HD89
Gene ID (Entrez): 56729
Immunogen: E.coli-derived Recombinant Human Resistin
Purification Method: Antigen affinity chromatography
Gene: RETN
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4
Gene Symbols: RETN
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Resistin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
Q9HD89
Gene ID (Entrez):
56729
Immunogen:
E.coli-derived Recombinant Human Resistin
Purification Method:
Antigen affinity chromatography
Gene:
RETN
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4
Gene Symbols:
RETN
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: MCP-1
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P14844
Gene ID (Entrez): 24770
Immunogen: E.coli-derived Recombinant Rat MCP-1 (CCL2)
Purification Method: Antigen affinity chromatography
Gene: Ccl2
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Gene Symbols: Ccl2
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
MCP-1
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P14844
Gene ID (Entrez):
24770
Immunogen:
E.coli-derived Recombinant Rat MCP-1 (CCL2)
Purification Method:
Antigen affinity chromatography
Gene:
Ccl2
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Gene Symbols:
Ccl2
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CD31 (PECAM-1)
Applications: Flow Cytometry
Conjugate: Brilliant Violet 711
Host Species: Rat
Target Species: Mouse
Gene Accession No.: Q08481
Gene ID (Entrez): 18613
Immunogen: __
Purification Method: Affinity chromatography
Gene: Pecam1
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Gene Symbols: Pecam1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
CD31 (PECAM-1)
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 711
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
Q08481
Gene ID (Entrez):
18613
Immunogen:
__
Purification Method:
Affinity chromatography
Gene:
Pecam1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Gene Symbols:
Pecam1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!