7245121
BDNF Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
BDNF
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human, Mouse, Rat
Gene Accession No.
P21237, P23363, P23560
Gene ID (Entrez)
12064, 24225, 627
Immunogen
E.coli-derived Recombinant Human/Murine/Rat BDNF
Purification Method
Antigen affinity chromatography
Gene
BDNF
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
abrineurin; ANON2; anorexia BDNF; Bdnf; BDNF precursor form; bdnf protein; brain derived neurothrophic factor; brain derived neurotrophic factor; brain-derived neurotrophic factor; BULN2; H-BDNF; neurotrophin; ProBDNF
Gene Symbols
BDNF
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human/Murine/Rat BDNF
- Anti-Human/Murine/Rat BDNF-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human BDNF by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human BDNF (500-P84) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human BDNF
- Western Blot: To detect hBDNF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hBDNF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P84BT-1MG will be provided as 2 x 500 μg BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family
- BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF
- Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form
- BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons
- Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated
- BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synaptic regulation
- BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain
- Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients, and may also play a role in the regulation of stress response and in the biology of mood disorders.
Compare Similar Items
Show Difference
Antigen: BDNF
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human, Mouse, Rat
Gene Accession No.: P21237, P23363, P23560
Gene ID (Entrez): 12064, 24225, 627
Immunogen: E.coli-derived Recombinant Human/Murine/Rat BDNF
Purification Method: Antigen affinity chromatography
Gene: BDNF
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: abrineurin; ANON2; anorexia BDNF; Bdnf; BDNF precursor form; bdnf protein; brain derived neurothrophic factor; brain derived neurotrophic factor; brain-derived neurotrophic factor; BULN2; H-BDNF; neurotrophin; ProBDNF
Gene Symbols: BDNF
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
BDNF
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human, Mouse, Rat
Gene Accession No.:
P21237, P23363, P23560
Gene ID (Entrez):
12064, 24225, 627
Immunogen:
E.coli-derived Recombinant Human/Murine/Rat BDNF
Purification Method:
Antigen affinity chromatography
Gene:
BDNF
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
abrineurin; ANON2; anorexia BDNF; Bdnf; BDNF precursor form; bdnf protein; brain derived neurothrophic factor; brain derived neurotrophic factor; brain-derived neurotrophic factor; BULN2; H-BDNF; neurotrophin; ProBDNF
Gene Symbols:
BDNF
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CD22 (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P20273
Gene ID (Entrez): 933
Immunogen: CHO cells-derived Recombinant Human sCD22
Purification Method: Antigen affinity chromatography
Gene: CD22
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Gene Symbols: CD22
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CD22 (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P20273
Gene ID (Entrez):
933
Immunogen:
CHO cells-derived Recombinant Human sCD22
Purification Method:
Antigen affinity chromatography
Gene:
CD22
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Gene Symbols:
CD22
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CCL6
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P27784
Gene ID (Entrez): 20305
Immunogen: E.coli-derived Recombinant Murine C10 (CCL6)
Purification Method: Antigen affinity chromatography
Gene: Ccl6
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: c10; CC chemokine C10; C-C motif chemokine 6; Ccl6; CCL6(22-95); CCL6(23-95); chemokine (C-C motif) ligand 6; chemokine ligand 6; Mrp-1; Protein C10; Scay6; Scya6; small inducible cytokine A6; small-inducible cytokine A6
Gene Symbols: Ccl6
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CCL6
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P27784
Gene ID (Entrez):
20305
Immunogen:
E.coli-derived Recombinant Murine C10 (CCL6)
Purification Method:
Antigen affinity chromatography
Gene:
Ccl6
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
c10; CC chemokine C10; C-C motif chemokine 6; Ccl6; CCL6(22-95); CCL6(23-95); chemokine (C-C motif) ligand 6; chemokine ligand 6; Mrp-1; Protein C10; Scay6; Scya6; small inducible cytokine A6; small-inducible cytokine A6
Gene Symbols:
Ccl6
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Maspin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P36952
Gene ID (Entrez): 5268
Immunogen: E.coli-derived Recombinant Human Maspin
Purification Method: Antigen affinity chromatography
Gene: SERPINB5
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 1110036M19Rik; AI462524; AI646751; Maspin; ovalbumin; peptidase inhibitor 5; PI5; PI-5; protease inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) peptidase inhibitor, clade B, member 5; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serine (or cysteine) proteinase inhibitor, clade B, member 5; serine protease inhibitor 7; serpin B5; serpin family B member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5; Spi5; Spi7
Gene Symbols: SERPINB5
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Maspin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P36952
Gene ID (Entrez):
5268
Immunogen:
E.coli-derived Recombinant Human Maspin
Purification Method:
Antigen affinity chromatography
Gene:
SERPINB5
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
1110036M19Rik; AI462524; AI646751; Maspin; ovalbumin; peptidase inhibitor 5; PI5; PI-5; protease inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) peptidase inhibitor, clade B, member 5; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serine (or cysteine) proteinase inhibitor, clade B, member 5; serine protease inhibitor 7; serpin B5; serpin family B member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5; Spi5; Spi7
Gene Symbols:
SERPINB5
Primary or Secondary:
Primary
Content And Storage:
-20°C