7245212
IFN gamma Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IFN gamma
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Rat
Gene Accession No.
P01581
Gene ID (Entrez)
25712
Immunogen
E.coli-derived Recombinant Rat IFN-gamma
Purification Method
Antigen affinity chromatography
Gene
IFNG
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
Gene Symbols
IFNG
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Rat IFN-gamma
- Anti-Rat IFN-gamma-specific antibody was purified by affinity chromatography employing an immobilized Rat IFN-gamma matrix
- Sandwich ELISA: To detect Rat IFN-gamma by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Rat IFN-gamma (500-P122Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat IFN-gamma
- Western Blot: To detect Rat IFN-gamma by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Rat IFN-gamma is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines
- IFN gamma is a dimeric protein consisting of two 146 amino acid subunits
- IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa
- On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation
- The biological activity of the IFN gamma homodimer is highly species specific
- Human IFN gamma does not show cross-reactivity with mouse
- IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes
- IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines
- Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway
- IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma
- IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN
- IFN gamma gene mutations are associated with aplastic anemia.
Compare Similar Items
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Antigen: IFN gamma
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P01581
Gene ID (Entrez): 25712
Immunogen: E.coli-derived Recombinant Rat IFN-gamma
Purification Method: Antigen affinity chromatography
Gene: IFNG
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
Gene Symbols: IFNG
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IFN gamma
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P01581
Gene ID (Entrez):
25712
Immunogen:
E.coli-derived Recombinant Rat IFN-gamma
Purification Method:
Antigen affinity chromatography
Gene:
IFNG
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
Gene Symbols:
IFNG
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: beta-5 Defensin
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q8NG35
Gene ID (Entrez): 245908, 504180
Immunogen: E.coli-derived Recombinant Human BD-5
Purification Method: Antigen affinity chromatography
Gene: DEFB105A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: __
Gene Symbols: DEFB105A, DEFB105B
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
beta-5 Defensin
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q8NG35
Gene ID (Entrez):
245908, 504180
Immunogen:
E.coli-derived Recombinant Human BD-5
Purification Method:
Antigen affinity chromatography
Gene:
DEFB105A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
__
Gene Symbols:
DEFB105A, DEFB105B
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: beta-Defensin 1
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P60022
Gene ID (Entrez): 1672
Immunogen: E.coli-derived Recombinant Human BD-1 (47 a.a.)
Purification Method: Antigen affinity chromatography
Gene: DEFB1
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: AW260221; BD1; BD-1; beta defensin 1; beta-defensin 1; beta-defensin-1; DEFB1; DEFB-1; DEFB101; defensin beta 1; defensin, beta 1; HBD1; rBD-1
Gene Symbols: DEFB1
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
beta-Defensin 1
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P60022
Gene ID (Entrez):
1672
Immunogen:
E.coli-derived Recombinant Human BD-1 (47 a.a.)
Purification Method:
Antigen affinity chromatography
Gene:
DEFB1
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
AW260221; BD1; BD-1; beta defensin 1; beta-defensin 1; beta-defensin-1; DEFB1; DEFB-1; DEFB101; defensin beta 1; defensin, beta 1; HBD1; rBD-1
Gene Symbols:
DEFB1
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: GDNF
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P39905
Gene ID (Entrez): 2668
Immunogen: E.coli-derived Recombinant Human GDNF
Purification Method: Antigen affinity chromatography
Gene: GDNF
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Gene Symbols: GDNF
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
GDNF
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P39905
Gene ID (Entrez):
2668
Immunogen:
E.coli-derived Recombinant Human GDNF
Purification Method:
Antigen affinity chromatography
Gene:
GDNF
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Gene Symbols:
GDNF
Primary or Secondary:
Primary
Content And Storage:
-20°C