7245386
p16INK4a-TAT Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
p16INK4a-TAT
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P42771
Gene ID (Entrez)
1029
Immunogen
E.coli-derived, 18.0 kDa Recombinant Human p16-INK4a-TAT
Purification Method
Antigen affinity chromatography
Gene
CDKN2A
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
p16INK4a
Gene Symbols
CDKN2A
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: EPAAGSSMEP SADWLATAAA RGRVEEVRAL LEAGALPNAP NSYGRRPIQV MMMGSARVAE LLLLHGAEPN CADPATLTRP VHDAAREGFL DTLVVLHRAG ARLDVRDAWG RLPVDLAEEL GHRDVARYLR AAAGGTRGSN HARIDAAEGP SDIPDGYGR KKRRQRRR
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human p16-INK4a-TAT
- Anti-Human p16-INK4a-TAT-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human p16-INK4a-TAT by sandwich ELISA (using 100 μL/well), a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody,in conjunction with PeproTech Polyclonal Anti-Human p16-INK4a-TAT (500-P284) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human p16-INK4a-TAT
- Western Blot: To detect Human p16-INK4a-TAT by Western Blot analysis, this antibody can be used at a concentration of 0.1-0.2 μg/mL.When used in conjunction with compatible development reagents, the detection limit for Recombinant Human p16-INK4a-TAT is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P284TBT-1MG will be provided as 2 x 500 μg p16-INK4a is a nuclear protein that regulates the cell cycle by inhibiting cyclin-dependent kinase-4 (CDK4) and CDK6
- p16-INK4a inhibits CDK activity by binding to the CDK molecules in a manner that interferes with their ability to interact with cyclin D
- This activity has the effect of suppressing tumor formation and growth, and of inducing replicative senescence in various normal cells, including stem cells
- The expression of p16-INK4a steadily increases with age, and tends to accumulate in stem cell compartments
- The deletion, rearrangement, or mutation of the p16-INK4a gene is frequently found in melanomas, as well as in certain other types of cancer
- p16-INK4a and other transcription factors have been introduced into cells by DNA transfection, viral infection, or microinjection
- Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other nuclear proteins into primary, as well as transformed, cells.
Compare Similar Items
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Antigen: p16INK4a-TAT
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P42771
Gene ID (Entrez): 1029
Immunogen: E.coli-derived, 18.0 kDa Recombinant Human p16-INK4a-TAT
Purification Method: Antigen affinity chromatography
Gene: CDKN2A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: p16INK4a
Gene Symbols: CDKN2A
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
p16INK4a-TAT
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P42771
Gene ID (Entrez):
1029
Immunogen:
E.coli-derived, 18.0 kDa Recombinant Human p16-INK4a-TAT
Purification Method:
Antigen affinity chromatography
Gene:
CDKN2A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
p16INK4a
Gene Symbols:
CDKN2A
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CD178 (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: P48023
Gene ID (Entrez): 356
Immunogen: CHO cells-derived Recombinant Human sFas Ligand
Purification Method: Antigen affinity chromatography
Gene: Faslg
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor
Gene Symbols: Faslg
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CD178 (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P48023
Gene ID (Entrez):
356
Immunogen:
CHO cells-derived Recombinant Human sFas Ligand
Purification Method:
Antigen affinity chromatography
Gene:
Faslg
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor
Gene Symbols:
Faslg
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: MIP-1 gamma
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P51670
Gene ID (Entrez): 20308
Immunogen: E.coli-derived Recombinant Murine MIP-1gamma (CCL9/10)
Purification Method: Antigen affinity chromatography
Gene: Ccl9
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C-C motif chemokine 9; CCF18; Ccl9; CCL9(29-101); CCL9(30-101); CCL9(31-101); chemokine (C-C motif) ligand 9; chemokine CCL9; macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; MIP-1 gamma; MIP-1-gamma; Mrp2; MRP-2; RP23-320E6.3; Scya10; Scya9; small inducible cytokine A10; small inducible cytokine A9; Small-inducible cytokine A9
Gene Symbols: Ccl9
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
MIP-1 gamma
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P51670
Gene ID (Entrez):
20308
Immunogen:
E.coli-derived Recombinant Murine MIP-1gamma (CCL9/10)
Purification Method:
Antigen affinity chromatography
Gene:
Ccl9
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C-C motif chemokine 9; CCF18; Ccl9; CCL9(29-101); CCL9(30-101); CCL9(31-101); chemokine (C-C motif) ligand 9; chemokine CCL9; macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; MIP-1 gamma; MIP-1-gamma; Mrp2; MRP-2; RP23-320E6.3; Scya10; Scya9; small inducible cytokine A10; small inducible cytokine A9; Small-inducible cytokine A9
Gene Symbols:
Ccl9
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Mycobacterium avium
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: M. avium cell extract.
Purification Method: Protein A
Gene: __
Concentration: 0.9 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: m avium; M. avium
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Mycobacterium avium
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
M. avium cell extract.
Purification Method:
Protein A
Gene:
__
Concentration:
0.9 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
m avium; M. avium
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles