89-934-257
HLA-A25/HLA-AW32 Mouse anti-Human, Clone: SPM418, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-934-257-Each-of-1 | In Stock | ₹ 64,426.68 |
89-934-257 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 64,426.68
GST (18%): ₹ 11,596.802
Total Price: ₹ 76,023.482
Antigen
HLA-A25/HLA-AW32
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias
HLAA
Host Species
Mouse
Purification Method
Protein A/G purification
Regulatory Status
RUO
Gene ID (Entrez)
3105/3106/3107
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone
SPM418
Description
Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.
Formulation
In 10mM PBS.
Gene Symbols
HLA-A
Immunogen
Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, DR2, DRw10.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
Content And Storage
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a κ
Related Products
Description
- HLA-C belongs to the HLA class I heavy chain paralogues
- This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
- The heavy chain is anchored in the membrane
- Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen
- They are expressed in nearly all cells
- The heavy chain is approximately 45 kDa and its gene contains 8 exons
- Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail
- Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
- Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- Over one hundred HLA-C alleles have been described [provided by RefSeq]
Compare Similar Items
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Antigen: HLA-A25/HLA-AW32
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: HLAA
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3105/3106/3107
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone: SPM418
Description: Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.
Formulation: In 10mM PBS.
Gene Symbols: HLA-A
Immunogen: Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, DR2, DRw10.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
Content And Storage: Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a κ
Antigen:
HLA-A25/HLA-AW32
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
HLAA
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3105/3106/3107
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone:
SPM418
Description:
Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.
Formulation:
In 10mM PBS.
Gene Symbols:
HLA-A
Immunogen:
Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, DR2, DRw10.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
Content And Storage:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2a κ
Antigen: HLA-A25/HLA-AW32
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: HLAA
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3105/3106/3107
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone: SPM417
Description: Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.
Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: HLA-A
Immunogen: Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, DR2, DRw10.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
Content And Storage: Store at 4°C.
Isotype: IgG2a κ
Antigen:
HLA-A25/HLA-AW32
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
HLAA
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3105/3106/3107
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone:
SPM417
Description:
Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.
Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
HLA-A
Immunogen:
Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, DR2, DRw10.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
Content And Storage:
Store at 4°C.
Isotype:
IgG2a κ
Antigen: HLA-B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3106
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence
Clone: SPM420
Description: Mouse monoclonal antibody raised against native human HLA-B.
Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: HLA-B
Immunogen: Normal human peripheral blood lymphocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage: Store at 4°C.
Isotype: IgG3 κ
Antigen:
HLA-B
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3106
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence
Clone:
SPM420
Description:
Mouse monoclonal antibody raised against native human HLA-B.
Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
HLA-B
Immunogen:
Normal human peripheral blood lymphocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage:
Store at 4°C.
Isotype:
IgG3 κ
Antigen: HLA-B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3106
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence
Clone: SPM420
Description: Mouse monoclonal antibody raised against native human HLA-B.
Formulation: In 10mM PBS.
Gene Symbols: HLA-B
Immunogen: Normal human peripheral blood lymphocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage: Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG3 κ
Antigen:
HLA-B
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3106
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence
Clone:
SPM420
Description:
Mouse monoclonal antibody raised against native human HLA-B.
Formulation:
In 10mM PBS.
Gene Symbols:
HLA-B
Immunogen:
Normal human peripheral blood lymphocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG3 κ