89-934-260
HLA-B Mouse anti-Human, Clone: SPM420, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-934-260-Each-of-1 | In Stock | ₹ 65,838.42 |
89-934-260 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 65,838.42
GST (18%): ₹ 11,850.916
Total Price: ₹ 77,689.336
Antigen
HLA-B
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species
Mouse
Purification Method
Protein A/G purification
Regulatory Status
RUO
Gene ID (Entrez)
3106
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence
Clone
SPM420
Description
Mouse monoclonal antibody raised against native human HLA-B.
Formulation
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols
HLA-B
Immunogen
Normal human peripheral blood lymphocytes.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage
Store at 4°C.
Isotype
IgG3 κ
Related Products
Description
- HLA-B belongs to the HLA class I heavy chain paralogues
- This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
- The heavy chain is anchored in the membrane
- Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen
- They are expressed in nearly all cells
- The heavy chain is approximately 45 kDa and its gene contains 8 exons
- Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail
- Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
- Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- Hundreds of HLA-B alleles have been described
- [provided by RefSeq]
Compare Similar Items
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Antigen: HLA-B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3106
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence
Clone: SPM420
Description: Mouse monoclonal antibody raised against native human HLA-B.
Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: HLA-B
Immunogen: Normal human peripheral blood lymphocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage: Store at 4°C.
Isotype: IgG3 κ
Antigen:
HLA-B
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3106
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence
Clone:
SPM420
Description:
Mouse monoclonal antibody raised against native human HLA-B.
Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
HLA-B
Immunogen:
Normal human peripheral blood lymphocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage:
Store at 4°C.
Isotype:
IgG3 κ
Antigen: HLA-B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3106
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence
Clone: SPM420
Description: Mouse monoclonal antibody raised against native human HLA-B.
Formulation: In 10mM PBS.
Gene Symbols: HLA-B
Immunogen: Normal human peripheral blood lymphocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage: Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG3 κ
Antigen:
HLA-B
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3106
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence
Clone:
SPM420
Description:
Mouse monoclonal antibody raised against native human HLA-B.
Formulation:
In 10mM PBS.
Gene Symbols:
HLA-B
Immunogen:
Normal human peripheral blood lymphocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Content And Storage:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG3 κ
Antigen: HLA-DP
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: DPB1/HLA-DP1B
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3115
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone: SPM421
Description: Mouse monoclonal antibody raised against native human HLA-DP.
Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: HLA-DPB1
Immunogen: Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
HLA-DP
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
DPB1/HLA-DP1B
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3115
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone:
SPM421
Description:
Mouse monoclonal antibody raised against native human HLA-DP.
Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
HLA-DPB1
Immunogen:
Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Antigen: HLA-DP
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: DPB1/HLA-DP1B
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 3115
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone: SPM421
Description: Mouse monoclonal antibody raised against native human HLA-DP.
Formulation: In 10mM PBS.
Gene Symbols: HLA-DPB1
Immunogen: Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Content And Storage: Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2b κ
Antigen:
HLA-DP
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
DPB1/HLA-DP1B
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3115
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone:
SPM421
Description:
Mouse monoclonal antibody raised against native human HLA-DP.
Formulation:
In 10mM PBS.
Gene Symbols:
HLA-DPB1
Immunogen:
Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Content And Storage:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2b κ