AB3849I
MilliporeSigma™ Rabbit anti-phospho- SMAD2 (Ser465/467), Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AB3849I-Each-of-1 | In Stock | ₹ 40,633.84 |
AB3849I - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,633.84
GST (18%): ₹ 7,314.091
Total Price: ₹ 47,947.931
Antigen
phospho- SMAD2 (Ser465/467)
Classification
Polyclonal
Gene Accession No.
Q15796
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Applications
Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
SMAD2; MADH2; MADR2
Immunogen
KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser465/467 of human Smad2.
Quantity
100 μg
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_005892
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Related Products
Description
- Specifically detects phospho- SMAD2 (Ser465/467) in Human samples, and it is validated for Western Blotting Mothers against decapentaplegic homolog 2 (UniProt Q15796; also known as hMAD-2, hSMAD2, JV18-1, MAD homolog 2, Mad-related protein 2, Mothers against DPP homolog 2, SMAD 2, SMAD family member 2, Smad2) is encoded by the SMAD2 (also known as MADH2, MADR2) gene (Gene ID 4087) in human
- Smad2 is a receptor-regulated intracellular signal transducer and transcriptional modulator activated by transforming growth factor TGF-beta and activin type 1 receptor kinases
- In response to TGF-beta signal, smad2 is recruited to the activated TGF-beta receptor through its interaction with the SMAD anchor for receptor activation (SARA) protein, where it is phosphorylated by the TGF-beta receptor
- The phosphorylation results in its dissociation from SARA and association with another family member smad4
- The smad2-smad4 complex then translocates into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- Smad2 can also be phosphorylated by activin type 1 receptor kinase, and thereby transduce activin-dependent signaling events.
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Antigen: phospho- SMAD2 (Ser465/467)
Classification: Polyclonal
Gene Accession No.: Q15796
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SMAD2; MADH2; MADR2
Immunogen: KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser465/467 of human Smad2.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_005892
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
phospho- SMAD2 (Ser465/467)
Classification:
Polyclonal
Gene Accession No.:
Q15796
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SMAD2; MADH2; MADR2
Immunogen:
KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser465/467 of human Smad2.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_005892
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
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