ABE1408MI

MilliporeSigma™ Rabbit anti-DNA polymerase beta, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABE1408MI-Each-of-1 In Stock ₹ 36,249.21

ABE1408MI - Each of 1

₹ 36,249.21

In Stock

Quantity

1

Base Price: ₹ 36,249.21

GST (18%): ₹ 6,524.858

Total Price: ₹ 42,774.068

Antigen

DNA polymerase beta

Classification

Polyclonal

Gene Accession No.

P06746

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

POLB

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human DNA polymerase beta.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NP_002681

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects DNA polymerase beta in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Western Blotting DNA polymerase beta (EC 2.7.7.7; UniProt P06746; also known as DNA pol beta, DNA polymerase beta subunit) is encoded by the POLB gene (Gene ID 5423) in human
  • DNA polymerase beta is involved in DNA recombination and base-excision repair (BER)
  • Upon oxidative DNA damage, Polb translocates to the nucleus, where it associates with AP endonuclease 1 (Apex) to carry out DNA repair
  • Apex makes a single nick 5′ to an abasic site in double-stranded DNA, Polb then inserts the replacement nucleotide(s)
  • Aberrant POLB overexpression results in an increased rate of spontaneous mutagenesis and a highly mutagenic tolerance phenotype
  • Thirty percent of all tumors are reported to harbor mutations in the POLB gene.

Compare Similar Items

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MilliporeSigma™

ABE1408MI

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Antigen:
DNA polymerase beta

Classification:
Polyclonal

Gene Accession No.:
P06746

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Applications:
Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
POLB

Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human DNA polymerase beta.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_002681

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Img

Fischer Scientific

ABE1409-25UG

--


Antigen:
Lysine-Specific Demethylase 4C (JMJD2C)

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Formulation:
__

Gene Symbols:
KDM4C,GASC1,JHDM3C,JMJD2C,KIAA0780

Immunogen:
KLH-Conjugated linear peptide corresponding to 18 amino acids from the N-terminal half of human Lysine-specific demethylase 4C.

Quantity:
25 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
__

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Img

Fischer Scientific

ABE1409MI

--


Antigen:
Lysine-Specific Demethylase 4C (JMJD2C)

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Applications:
Immunohistochemistry (Paraffin), Western Blot

Formulation:
__

Gene Symbols:
KDM4C,GASC1,JHDM3C,JMJD2C,KIAA0780

Immunogen:
KLH-Conjugated linear peptide corresponding to 18 amino acids from the N-terminal half of human Lysine-specific demethylase 4C.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_055876

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Img

MilliporeSigma

ABE1413MI

--


Antigen:
phospho Histone H3 (Tyr41)

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Dot Blot, Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ

Immunogen:
KLH-conjugated linear peptide corresponding to human phospho Histone H3 (Tyr41) near the N-terminus.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_003520

Content And Storage:
2-8°C for 12 months