ABE1408MI
MilliporeSigma™ Rabbit anti-DNA polymerase beta, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1408MI-Each-of-1 | In Stock | ₹ 36,249.21 |
ABE1408MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,249.21
GST (18%): ₹ 6,524.858
Total Price: ₹ 42,774.068
Antigen
DNA polymerase beta
Classification
Polyclonal
Gene Accession No.
P06746
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
POLB
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human DNA polymerase beta.
Quantity
100 μg
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_002681
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
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Description
- Specifically detects DNA polymerase beta in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Western Blotting DNA polymerase beta (EC 2.7.7.7; UniProt P06746; also known as DNA pol beta, DNA polymerase beta subunit) is encoded by the POLB gene (Gene ID 5423) in human
- DNA polymerase beta is involved in DNA recombination and base-excision repair (BER)
- Upon oxidative DNA damage, Polb translocates to the nucleus, where it associates with AP endonuclease 1 (Apex) to carry out DNA repair
- Apex makes a single nick 5′ to an abasic site in double-stranded DNA, Polb then inserts the replacement nucleotide(s)
- Aberrant POLB overexpression results in an increased rate of spontaneous mutagenesis and a highly mutagenic tolerance phenotype
- Thirty percent of all tumors are reported to harbor mutations in the POLB gene.
Compare Similar Items
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Antigen: DNA polymerase beta
Classification: Polyclonal
Gene Accession No.: P06746
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Applications: Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: POLB
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human DNA polymerase beta.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_002681
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
DNA polymerase beta
Classification:
Polyclonal
Gene Accession No.:
P06746
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Applications:
Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
POLB
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human DNA polymerase beta.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_002681
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: Lysine-Specific Demethylase 4C (JMJD2C)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Applications: Western Blot, Immunohistochemistry (Paraffin)
Formulation: __
Gene Symbols: KDM4C,GASC1,JHDM3C,JMJD2C,KIAA0780
Immunogen: KLH-Conjugated linear peptide corresponding to 18 amino acids from the N-terminal half of human Lysine-specific demethylase 4C.
Quantity: 25 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
Lysine-Specific Demethylase 4C (JMJD2C)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Formulation:
__
Gene Symbols:
KDM4C,GASC1,JHDM3C,JMJD2C,KIAA0780
Immunogen:
KLH-Conjugated linear peptide corresponding to 18 amino acids from the N-terminal half of human Lysine-specific demethylase 4C.
Quantity:
25 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: Lysine-Specific Demethylase 4C (JMJD2C)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Applications: Immunohistochemistry (Paraffin), Western Blot
Formulation: __
Gene Symbols: KDM4C,GASC1,JHDM3C,JMJD2C,KIAA0780
Immunogen: KLH-Conjugated linear peptide corresponding to 18 amino acids from the N-terminal half of human Lysine-specific demethylase 4C.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_055876
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
Lysine-Specific Demethylase 4C (JMJD2C)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Applications:
Immunohistochemistry (Paraffin), Western Blot
Formulation:
__
Gene Symbols:
KDM4C,GASC1,JHDM3C,JMJD2C,KIAA0780
Immunogen:
KLH-Conjugated linear peptide corresponding to 18 amino acids from the N-terminal half of human Lysine-specific demethylase 4C.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_055876
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: phospho Histone H3 (Tyr41)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Applications: Dot Blot, Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ
Immunogen: KLH-conjugated linear peptide corresponding to human phospho Histone H3 (Tyr41) near the N-terminus.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_003520
Content And Storage: 2-8°C for 12 months
Antigen:
phospho Histone H3 (Tyr41)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Dot Blot, Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ
Immunogen:
KLH-conjugated linear peptide corresponding to human phospho Histone H3 (Tyr41) near the N-terminus.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_003520
Content And Storage:
2-8°C for 12 months